SCHEMBL9404591

SCHEMBL9404591

C=CCc1cc(Cc2ccccc2)cc(CC=C)c1O

nearest known ligand 0.50

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 3/20 0.50
PTPN2 P17706 1/20 0.50
PTPN6 P29350 1/20 0.50
GABRA1 P14867 2/20 0.46
GABRB2 P47870 2/20 0.46
BCL2 P10415 1/20 0.46
BCL2L1 Q07817 1/20 0.46
IDH1 O75874 1/20 0.43
CALM1 P0DP23 1/20 0.43
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
DHFR P00374 1/20 0.42
ALOX5 P09917 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9765498 0.90 PTPN1 (0.47) PTPN1PTPN2PTPN6GABRA1GABRB2
SCHEMBL9489328 0.89 DHFR (0.48) GABRA1GABRB2MEN1KMT2ADHFR
SCHEMBL9287678 0.87 DHFR (0.47) GABRA1GABRB2MEN1KMT2ADHFR
SCHEMBL9516559 0.86 PTPN1 (0.73) PTPN1PTPN2PTPN6MEN1KMT2A
SCHEMBL9804631 0.86 PTPN1 (0.50) PTPN1PTPN2PTPN6BCL2BCL2L1
SCHEMBL7121491 0.83 IDH1 (0.58) GABRA1GABRB2BCL2BCL2L1IDH1
SCHEMBL4224884 0.82 GABRA1 (0.59) GABRA1GABRB2BCL2BCL2L1MEN1
SCHEMBL9204214 0.82 AKR1B1 (0.61) PTPN1GABRA1GABRB2MEN1KMT2A
SCHEMBL9804555 0.81 PTPN1 (0.70) PTPN1PTPN2PTPN6BCL2BCL2L1
SCHEMBL9174306 0.81 PTPN1 (0.70) PTPN1PTPN2PTPN6BCL2BCL2L1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0376466-B1 Solvent-free solid polymer electrolyte and process for its preparation ASS UNIVERSITIES INC (US) 1994-06-22 EP disclosed
EP-0376466-A2 Solvent-free solid polymer electrolyte and process for its preparation ASSOCIATED UNIVERSITIES, INC. (US) 1990-07-04 EP disclosed
US-4882243-A SOLVENT-FREE, BATTERIES POLYTECHNIC UNIVERSITY (US) 1989-11-21 US disclosed
EP-0065289-A1 Process for the synthesis of trialkyl-tris(3,5-dialkyl-4-hydroxybenzyl) benzene ETHYL CORPORATION (US) 1982-11-24 EP disclosed