SCHEMBL9765498

SCHEMBL9765498

C=CCc1cc(CC=C)c(O)c(Cc2ccccc2)c1

nearest known ligand 0.52

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 3/20 0.47
PTPN2 P17706 1/20 0.47
PTPN6 P29350 1/20 0.47
BCL2 P10415 1/20 0.47
BCL2L1 Q07817 1/20 0.47
GABRA1 P14867 1/20 0.43
GABRB2 P47870 1/20 0.43
ALOX5 P09917 1/20 0.42
EGFR P00533 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9804631 0.97 PTPN1 (0.50) PTPN1PTPN2PTPN6BCL2BCL2L1
SCHEMBL9404591 0.90 PTPN1 (0.50) PTPN1PTPN2PTPN6BCL2BCL2L1
SCHEMBL2461750 0.84 XDH (0.48) GABRA1GABRB2ALOX5
SCHEMBL4224884 0.83 GABRA1 (0.59) BCL2BCL2L1GABRA1GABRB2
2-Allylphenol SCHEMBL9576190 0.81 AKR1B1 (0.49) GABRA1GABRB2ALOX5
SCHEMBL10688359 0.80 XDH (0.58) BCL2BCL2L1GABRA1GABRB2ALOX5
SCHEMBL12277261 0.80 GABRA1 (0.56) GABRA1GABRB2
SCHEMBL11660795 0.78 DHFR (0.46) GABRA1GABRB2ALOX5
SCHEMBL9804555 0.78 PTPN1 (0.70) PTPN1PTPN2PTPN6BCL2BCL2L1
SCHEMBL9174306 0.78 PTPN1 (0.70) PTPN1PTPN2PTPN6BCL2BCL2L1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0438378-A1 Substituted diallylphenol derivatives as reactive diluents for bismaleimides CIBA-GEIGY AG (CH) 1991-07-24 EP disclosed
US-5025095-A For toughness and workability in curable coatings, prpregs, composites, laminates CIBA-GEIGY CORPORATION (US) 1991-06-18 US disclosed
EP-0065289-A1 Process for the synthesis of trialkyl-tris(3,5-dialkyl-4-hydroxybenzyl) benzene ETHYL CORPORATION (US) 1982-11-24 EP disclosed