Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | MMP3 | P08254 | 3/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | LTA4H | P09960 | 3/20 | 0.49 |
| ▸ | HRH2 | P25021 | 1/20 | 0.49 |
| ▸ | HRH1 | P35367 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
| ▸ | MMP1 | P03956 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
| ▸ | MMP13 | P45452 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MGLL | Q99685 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6328916 | 0.87 | MAPT (0.55) | MAPTSMN1; SMN2MMP3HDAC1HDAC2 | |
| SCHEMBL1285386 | 0.83 | MMP2 (0.61) | MAPTMMP3HDAC1HDAC2LTA4H | |
| SCHEMBL1285929 | 0.83 | MMP2 (0.61) | MAPTMMP3HDAC1HDAC2LTA4H | |
| SCHEMBL7301892 | 0.83 | MMP3 (0.57) | MAPTSMN1; SMN2MMP3HDAC1HDAC2 | |
| SCHEMBL15970987 | 0.83 | MMP2 (0.59) | MAPTMMP3HDAC1HDAC2LTA4H | |
| 4-Cyanophenol SCHEMBL8993981 | 0.82 | CYSLTR2 (0.51) | MAPTMMP3HDAC1HDAC2LTA4H | |
| SCHEMBL6336869 | 0.82 | HDAC1 (0.58) | MAPTSMN1; SMN2MMP3HDAC1HDAC2 | |
| SCHEMBL5522757 | 0.82 | HDAC1 (0.58) | MAPTSMN1; SMN2MMP3HDAC1HDAC2 | |
| SCHEMBL7717980 | 0.80 | PPARD (0.51) | MAPTSMN1; SMN2MMP3HDAC1HDAC2 | |
| SCHEMBL7717978 | 0.80 | PPARD (0.51) | MAPTSMN1; SMN2MMP3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-6279389-A | — | — | None | — | — | JP | disclosed |
| JP-H06279389-A | AMIDINOPHENYL ETHER DERIVATIVE | TERUMO CORP | 1994-10-04 | — | — | JP | disclosed |