Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 9/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.48 |
| ▸ | CCR6 | P51684 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9404915 | 0.99 | KMT2A (0.51) | KMT2AHSD17B10MAPK1HSP90AA1CCR6 | |
| SCHEMBL9404994 | 0.83 | KMT2A (0.53) | KMT2AMAPK1L3MBTL1LMNACYP1A2 | |
| Hydrochloric Acid SCHEMBL16049971 | 0.82 | KMT2A (0.52) | KMT2AMAPK1L3MBTL1LMNACYP1A2 | |
| Hydrochloric Acid SCHEMBL9586335 | 0.82 | LMNA (0.54) | KMT2AHSD17B10MAPK1L3MBTL1LMNA | |
| SCHEMBL9404972 | 0.82 | MAPK1 (0.57) | KMT2AHSD17B10MAPK1HSP90AA1CCR6 | |
| SCHEMBL9404946 | 0.81 | MAPK1 (0.56) | KMT2AHSD17B10MAPK1HSP90AA1L3MBTL1 | |
| SCHEMBL9404951 | 0.81 | MAPK1 (0.56) | KMT2AHSD17B10MAPK1HSP90AA1CCR6 | |
| SCHEMBL9405005 | 0.81 | PKM (0.62) | KMT2AL3MBTL1ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL11637183 | 0.81 | KMT2A (0.51) | KMT2AHSD17B10MAPK1HSP90AA1CCR6 | |
| SCHEMBL9405029 | 0.81 | KMT2A (0.44) | KMT2AMAPK1LMNAALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0431942-B1 | Percutaneously absorbable pharmaceutical preparation containing dopamine derivative | SANSHO CO (JP) | 1994-03-23 | — | — | EP | disclosed |
| US-5246949-A | And lactic acid esters, treatment of hypotension and cardiac circulatory insufficiency | SANSHO CO., LTD. (JP) | 1993-09-21 | — | — | US | disclosed |
| EP-0431942-A2 | Percutaneously absorbable pharmaceutical preparation containing dopamine derivative | SANSHO CO., LTD. (JP) | 1991-06-12 | — | — | EP | disclosed |