Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.45 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | CCR6 | P51684 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9404946 | 0.92 | MAPK1 (0.56) | MAPK1HSD17B10KMT2ALMNAALDH1A1 | |
| SCHEMBL9404860 | 0.85 | ADRB2 (0.55) | KMT2AALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL9404951 | 0.85 | MAPK1 (0.56) | MAPK1HSD17B10KMT2ALMNAALDH1A1 | |
| SCHEMBL9404933 | 0.84 | ADRB2 (0.43) | MAPK1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL9404867 | 0.84 | PKM (0.60) | MAPK1KMT2AALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL9404871 | 0.82 | KMT2A (0.52) | MAPK1HSD17B10KMT2ALMNAALDH1A1 | |
| Hydrochloric Acid SCHEMBL9404915 | 0.81 | KMT2A (0.51) | MAPK1HSD17B10KMT2ALMNAALDH1A1 | |
| SCHEMBL9404862 | 0.79 | ADRB2 (0.56) | KMT2AALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9011269 | 0.78 | MAPK1 (0.76) | MAPK1KMT2ALMNACYP1A2NPC1 | |
| SCHEMBL9404877 | 0.78 | NPC1 (0.47) | MAPK1KMT2ALMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0431942-B1 | Percutaneously absorbable pharmaceutical preparation containing dopamine derivative | SANSHO CO (JP) | 1994-03-23 | — | — | EP | disclosed |
| US-5246949-A | And lactic acid esters, treatment of hypotension and cardiac circulatory insufficiency | SANSHO CO., LTD. (JP) | 1993-09-21 | — | — | US | disclosed |
| EP-0431942-A2 | Percutaneously absorbable pharmaceutical preparation containing dopamine derivative | SANSHO CO., LTD. (JP) | 1991-06-12 | — | — | EP | disclosed |