Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL35319498 | 0.97 | ALDH1A1 (0.41) | ALDH1A1TSHRHIF1AALOX15KDM4E | |
| Hydrochloric Acid SCHEMBL28633975 | 0.94 | ALDH1A1 (0.39) | ALDH1A1TSHRHIF1AALOX15KDM4E | |
| Iodide SCHEMBL26969679 | 0.94 | ALDH1A1 (0.39) | ALDH1A1TSHRHIF1AALOX15KDM4E | |
| Bromide SCHEMBL2450382 | 0.94 | ALDH1A1 (0.39) | ALDH1A1TSHRHIF1AALOX15KDM4E | |
| Phosphine SCHEMBL28255509 | 0.92 | ALDH1A1 (0.38) | ALDH1A1TSHRHIF1AALOX15KDM4E | |
| SCHEMBL31634029 | 0.87 | ALDH1A1 (0.35) | ALDH1A1TSHRHIF1AALOX15KDM4E | |
| Bromide SCHEMBL2448830 | 0.73 | HIF1A (0.43) | ALDH1A1TSHRHIF1AMAPTTDP1 | |
| Bromide SCHEMBL20555667 | 0.72 | TSHR (0.39) | ALDH1A1TSHRHIF1AALOX15KDM4E | |
| Bromide SCHEMBL7877086 | 0.72 | TSHR (0.35) | ALDH1A1TSHRHIF1AALOX15 | |
| Bromide SCHEMBL7877084 | 0.72 | TSHR (0.35) | ALDH1A1TSHRHIF1AALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0160824-B2 | Reaction product of olefinically unsaturated compounds with active hydrogen compounds, process for their preparation and 2-component coating systems based thereon | HOECHST AG (DE) | 1994-08-03 | — | — | EP | disclosed |
| US-5084536-A | Reaction product of olefinically unsaturated compounds with compounds containing active hydrogen, processes for their preparation and 2-component lacquers based thereon | HOECHST AG (DE) | 1992-01-28 | — | — | US | disclosed |
| US-4871822-A | Reaction product of olefinically unsaturated compounds with compounds containing active hydrogen, processes for their preparation and 2-component lacquers based thereon HOE 85/F O36J | HOECHST AG (DE) | 1989-10-03 | — | — | US | disclosed |
| EP-0160824-B1 | REACTION PRODUCT OF OLEFINICALLY UNSATURATED COMPOUNDS WITH ACTIVE HYDROGEN COMPOUNDS, PROCESS FOR THEIR PREPARATION AND 2-COMPONENT COATING SYSTEMS BASED THEREON | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-09-06 | — | — | EP | disclosed |
| EP-0160824-A1 | Reaction product of olefinically unsaturated compounds with active hydrogen compounds, process for their preparation and 2-component coating systems based thereon | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-11-13 | — | — | EP | disclosed |