Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL35319498 | 0.97 | ALDH1A1 (0.41) | ALDH1A1TSHRHIF1AALOX15KDM4E | |
| Bromide SCHEMBL2450382 | 0.94 | ALDH1A1 (0.39) | ALDH1A1TSHRHIF1AALOX15KDM4E | |
| Iodide SCHEMBL26969679 | 0.94 | ALDH1A1 (0.39) | ALDH1A1TSHRHIF1AALOX15KDM4E | |
| Fluoride Ion SCHEMBL9405342 | 0.94 | ALDH1A1 (0.39) | ALDH1A1TSHRHIF1AALOX15KDM4E | |
| Phosphine SCHEMBL28255509 | 0.92 | ALDH1A1 (0.38) | ALDH1A1TSHRHIF1AALOX15KDM4E | |
| SCHEMBL31634029 | 0.87 | ALDH1A1 (0.35) | ALDH1A1TSHRHIF1AALOX15KDM4E | |
| Bromide SCHEMBL2448830 | 0.73 | HIF1A (0.43) | ALDH1A1TSHRHIF1AMAPTTDP1 | |
| Bromide SCHEMBL20555667 | 0.72 | TSHR (0.39) | ALDH1A1TSHRHIF1AALOX15KDM4E | |
| Hydrochloric Acid SCHEMBL10574802 | 0.72 | ALDH1A1 (0.39) | ALDH1A1TSHRHIF1ATDP1CYP2C19 | |
| Bromide SCHEMBL7877086 | 0.72 | TSHR (0.35) | ALDH1A1TSHRHIF1AALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113387968-A | Ultraviolet radiation resistant phenylphosphine counter cation type rare earth complex and preparation method thereof | 河北工业大学 | 2021-09-14 | — | — | CN | disclosed |