Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphine SCHEMBL28255509 | 0.97 | ALDH1A1 (0.38) | ALDH1A1TSHRHIF1AALOX15KDM4E | |
| SCHEMBL35319498 | 0.97 | ALDH1A1 (0.41) | ALDH1A1TSHRHIF1AALOX15KDM4E | |
| Iodide SCHEMBL26969679 | 0.94 | ALDH1A1 (0.39) | ALDH1A1TSHRHIF1AALOX15KDM4E | |
| Hydrochloric Acid SCHEMBL28633975 | 0.94 | ALDH1A1 (0.39) | ALDH1A1TSHRHIF1AALOX15KDM4E | |
| Fluoride Ion SCHEMBL9405342 | 0.94 | ALDH1A1 (0.39) | ALDH1A1TSHRHIF1AALOX15KDM4E | |
| SCHEMBL31634029 | 0.87 | ALDH1A1 (0.35) | ALDH1A1TSHRHIF1AALOX15KDM4E | |
| Bromide SCHEMBL2448830 | 0.79 | HIF1A (0.43) | ALDH1A1TSHRHIF1AMAPTTDP1 | |
| Bromide SCHEMBL20555667 | 0.78 | TSHR (0.39) | ALDH1A1TSHRHIF1AALOX15KDM4E | |
| Bromide SCHEMBL7877086 | 0.77 | TSHR (0.35) | ALDH1A1TSHRHIF1AALOX15 | |
| Bromide SCHEMBL7877084 | 0.77 | TSHR (0.35) | ALDH1A1TSHRHIF1AALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 396 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12589384-B2 | Non-metal catalyst for synthesizing polycarbonate by CO2 and preparation method therefor | WUHAN INSTITUTE OF TECHNOLOGY (CN) | 2026-03-31 | — | — | US | claimed |
| EP-4673399-A1 | A LIQUID PHASE EXFOLIATION METHOD AND AN EXFOLIATING MEDIUM | Centrum pre vyuzitie pokrocilych materialov Slovenskej akademie vied, verejna vyskumna institucia (SK) | 2026-01-07 | — | — | EP | claimed |
| WO-2024181933-A1 | A LIQUID PHASE EXFOLIATION METHOD AND AN EXFOLIATING MEDIUM | CENTRUM PRE VYUZITIE POKROCILYCH MATERIALOV SLOVENSKEJ AKADEMIE VIED, VEREJNA VYSKUMNA INSTITUCIA (SK) | 2024-09-06 | — | — | WO | claimed |
| CN-114394991-B | Method for catalytic synthesis of vinyl trichlorosilane | 浙江锦华新材料股份有限公司 | 2024-08-13 | — | — | CN | claimed |
| CN-118373999-A | Synthesis method of low-molecular-weight hydroxyl silicone oil with controllable molecular weight | 上海普信高分子材料有限公司 | 2024-07-23 | — | — | CN | claimed |
| US-20230415138-A1 | NON-METAL CATALYST FOR SYNTHESIZING POLYCARBONATE BY CO2 AND PREPARATION METHOD THEREFOR | WUHAN INSTITUTE OF TECHNOLOGY (CN) | 2023-12-28 | — | — | US | claimed |
| US-20230100363-A1 | MOLECULARLY IMPRINTED POLYMERS FOR EXTRACTION OF CANNABINOIDS AND USES THEREOF | ORCA HOLDINGS, LLC | 2023-03-30 | — | — | US | claimed |
| CN-114933698-A | For CO 2 Non-metal catalyst for synthesizing polycarbonate and preparation method thereof | 武汉工程大学 | 2022-08-23 | — | — | CN | claimed |
| US-20220177666-A1 | MOLECULARLY IMPRINTED POLYMERS FOR EXTRACTION OF CANNABINOIDS AND USES THEREOF | ORCA HOLDINGS, LLC | 2022-06-09 | — | — | US | claimed |
| CN-114394991-A | Method for catalytically synthesizing vinyl trichlorosilane | 浙江锦华新材料股份有限公司 | 2022-04-26 | — | — | CN | claimed |
| US-5563014-A | SOFTENABLE LAYER CONTAINIG PHOTOSENSITIVE MARKING MATERIAL; TRANSPARENTIZING AGENT | XEROX CORPORATION (US) | 1996-10-08 | — | — | US | claimed |
| US-5531900-A | FOR REMOVING NEGATIVELY CHARGED MACROMOLECULAR AND COLLOIDAL CONTAMINANATS | UNIVERSITY OF ARIZONA (US) | 1996-07-02 | — | — | US | claimed |
| US-5514505-A | SELECTIVE TRANSPARENTIZATION OF PHOTOSENSITIVE MIGRATION MARKING PARTICLES EMBEDDED NEAR THE SURFACE OF A SOFTENABLE LAYER SUPPORTED BY AN ELECTROCONDUCTIVE SUBSTRATE | XEROX CORPORATION (US) | 1996-05-07 | — | — | US | claimed |
| US-5456767-A | Polymerization activated by oxygen corrosion of ferrous metal forming protective coating | PETROLITE CORPORATION (US) | 1995-10-10 | — | — | US | claimed |
| EP-0615853-A1 | Recording sheets containing phosphonium compounds | XEROX CORPORATION (US) | 1994-09-21 | — | — | EP | claimed |
| US-4859458-A | Hair conditioning polymers containing alkoxylated nitrogen salts of sulfonic acid | MORTON THIOKOL, INC. (US) | 1989-08-22 | — | — | US | claimed |
| US-4842712-A | LIQUID DISTRIBUTORS OF CELLULOSE LONG FIBER NONWOVEN FABRIC | FUJI PHOTO FILM CO., LTD. (JP) | 1989-06-27 | — | — | US | claimed |
| EP-0231033-A2 | Device for measuring ion activity | FUJI PHOTO FILM CO., LTD. (JP) | 1987-08-05 | — | — | EP | claimed |
| US-4578267-A | ALKOXYLATED NITROGEN SALTS MODIFIED ADDITION POLYMERS | MORTON THIOKOL, INC. (US) | 1986-03-25 | — | — | US | claimed |
| US-4401650-A | Skin conditioning polymers containing alkoxylated nitrogen salts of sulfonic acid | THIOKOL CORPORATION (US) | 1983-08-30 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230100363-A1 | MOLECULARLY IMPRINTED POLYMERS FOR EXTRACTION OF CANNABINOIDS AND USES THEREOF | CNR2, CNR1, CDIPT | ALDH1A1 3487/4885TSHR 4448/4885HIF1A 3495/4885 |
| US-20220177666-A1 | MOLECULARLY IMPRINTED POLYMERS FOR EXTRACTION OF CANNABINOIDS AND USES THEREOF | CNR2, CNR1, CDIPT | ALDH1A1 3487/4885TSHR 4448/4885HIF1A 3495/4885 |
| US-12589384-B2 | Non-metal catalyst for synthesizing polycarbonate by CO2 and preparation method therefor | PIK3CD, PIK3C2B, PIK3C2A | ALDH1A1 3553/4885TSHR 2488/4885HIF1A 697/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.