Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9533588 | 0.75 | NAAA (0.43) | CTNNB1KDM4ERECQL | |
| SCHEMBL9124855 | 0.73 | CTNNB1 (0.31) | CTNNB1 | |
| SCHEMBL12384145 | 0.73 | CTNNB1 (0.42) | CTNNB1KDM4ERECQL | |
| SCHEMBL9561939 | 0.71 | CTNNB1 (0.34) | CTNNB1CACNA1H | |
| SCHEMBL10220198 | 0.71 | CA1 (0.37) | — | |
| SCHEMBL3614998 | 0.70 | CHRNB2 (0.39) | CTNNB1 | |
| SCHEMBL9369921 | 0.70 | KCNA3 (0.50) | RECQL | |
| SCHEMBL9120103 | 0.69 | — | — | |
| SCHEMBL9079873 | 0.69 | CTNNB1 (0.39) | CTNNB1KDM4ERECQL | |
| SCHEMBL9079842 | 0.69 | CTNNB1 (0.36) | CTNNB1KDM4ERECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5356898-A | Antiinflammatory agents, antiallergens, antiulcer agents | WARNER-LAMBERT COMPANY (US) | 1994-10-18 | — | — | US | disclosed |
| US-5340815-A | Inhibitors of 5-lipoxygenase and/or cyclooxygenase | WARNER-LAMBERT COMPANY (US) | 1994-08-23 | — | — | US | disclosed |
| EP-0569493-A4 | SUBSTITUTED 4,6-DI-TERTIARY-BUTYL-5-HYDROXY-PYRIMIDINES | — | 1993-11-24 | — | — | EP | disclosed |
| EP-0569491-A1 | 2-SUBSTITUTED-4,6-DI-TERTIARY-BUTYL-5-HYDROXY-1,3-PYRIMIDINES USEFUL AS ANTIINFLAMMATORY AGENTS | WARNER-LAMBERT COMPANY (US) | 1993-11-18 | — | — | EP | disclosed |
| EP-0569493-A1 | SUBSTITUTED 4,6-DI-TERTIARY-BUTYL-5-HYDROXY-PYRIMIDINES | WARNER-LAMBERT COMPANY (US) | 1993-11-18 | — | — | EP | disclosed |
| WO-1992013536-A1 | 2-SUBSTITUTED-4,6-DI-TERTIARY-BUTYL-5-HYDROXY-1,3-PYRIMIDINES USEFUL AS ANTIINFLAMMATORY AGENTS | WARNER-LAMBERT COMPANY (US) | 1992-08-20 | — | — | WO | disclosed |