Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.43 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9405597 | 0.75 | CTNNB1 (0.33) | CTNNB1KDM4ERECQL | |
| SCHEMBL9405569 | 0.74 | FGFR4 (0.31) | — | |
| SCHEMBL21880671 | 0.73 | NAAA (0.53) | NAAAKDM4EALDH1A1LMNAHTT | |
| SCHEMBL2185557 | 0.72 | NAAA (0.42) | NAAAKDM4EALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL12384145 | 0.72 | CTNNB1 (0.42) | CTNNB1KDM4ERECQLALDH1A1 | |
| SCHEMBL25672409 | 0.72 | NAAA (0.55) | NAAAKDM4EALDH1A1LMNAHTT | |
| SCHEMBL4750637 | 0.71 | TBXAS1 (0.46) | SMN1; SMN2 | |
| SCHEMBL4996156 | 0.70 | PKM (0.40) | CTNNB1KDM4ERECQL | |
| SCHEMBL25319490 | 0.69 | NAAA (0.53) | NAAAALDH1A1LMNAGLAHTT | |
| SCHEMBL3159666 | 0.69 | CTNNB1 (0.39) | CTNNB1KDM4ERECQLALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0569491-A1 | 2-SUBSTITUTED-4,6-DI-TERTIARY-BUTYL-5-HYDROXY-1,3-PYRIMIDINES USEFUL AS ANTIINFLAMMATORY AGENTS | WARNER-LAMBERT COMPANY (US) | 1993-11-18 | — | — | EP | disclosed |
| WO-1992013536-A1 | 2-SUBSTITUTED-4,6-DI-TERTIARY-BUTYL-5-HYDROXY-1,3-PYRIMIDINES USEFUL AS ANTIINFLAMMATORY AGENTS | WARNER-LAMBERT COMPANY (US) | 1992-08-20 | — | — | WO | disclosed |