SCHEMBL940640

SCHEMBL940640

CO[Si](OC)(OC)c1ccc(C)cc1Cl

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.36
MAPT P10636 9/20 0.36
L3MBTL1 Q9Y468 8/20 0.36
HPGD P15428 5/20 0.36
ALDH1A1 P00352 3/20 0.36
KMT2A Q03164 3/20 0.36
MAPK1 P28482 2/20 0.36
MEN1 O00255 2/20 0.36
CYP2C9 P11712 2/20 0.36
CYP2C19 P33261 2/20 0.36
USP2 O75604 1/20 0.36
POLB P06746 1/20 0.36
ALOX12 P18054 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
ACHE P22303 1/20 0.35
THRB P10828 1/20 0.34
RAB9A P51151 5/20 0.33
NPC1 O15118 3/20 0.33
SMN1; SMN2 Q16637 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13027790 0.80 ACHE (0.39) HPGDALDH1A1TDP1ACHETHRB
SCHEMBL3109782 0.80 TDP1 (0.41) LMNAHPGDALDH1A1MAPK1TDP1
SCHEMBL13027103 0.79 ACHE (0.56) LMNAMAPTL3MBTL1HPGDALDH1A1
SCHEMBL28050518 0.76 LMNA (0.39) LMNAMAPTL3MBTL1HPGDALDH1A1
SCHEMBL29344114 0.76 LMNA (0.39) LMNAMAPTL3MBTL1HPGDALDH1A1
SCHEMBL730148 0.75 ACHE (0.35) ALDH1A1ACHECYP1A2CYP3A4
SCHEMBL27893479 0.75 NPSR1 (0.41) LMNAMAPTL3MBTL1HPGDALDH1A1
SCHEMBL17966489 0.74 LMNA (0.38) LMNAMAPTL3MBTL1HPGDALDH1A1
SCHEMBL13027083 0.74 ALDH1A1 (0.39) LMNAMAPTHPGDALDH1A1TDP1
SCHEMBL241494 0.71 TSHR (0.41) LMNAMAPTL3MBTL1HPGDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1782436-B1 METHOD FOR TREATING ELECTRICAL CABLE AT SUSTAINED ELEVATED PRESSURE NOVINIUM INC (US) 2017-05-31 EP disclosed
EP-2121273-B1 ACID-CATALYZED DIELECTRIC ENHANCEMENT FLUID AND CABLE RESTORATION METHOD EMPLOYING SAME NOVINIUM INC (US) 2014-06-25 EP disclosed
US-8656586-B2 Method for treating electrical cable at sustained elevated pressure NOVINIUM, INC. (US) 2014-02-25 US disclosed
US-8394737-B2 Preparation of activating supports TOTAL PETROCHEMICALS RESEARCH FELUY Seneffe (BE) 2013-03-12 US disclosed
EP-1744866-B1 METHOD FOR SELECTING FORMULATIONS TO TREAT ELECTRICAL CABLES NOVINIUM INC (US) 2012-08-08 EP disclosed
US-8205326-B2 Method for treating electrical cable at sustained elevated pressure NOVINIUM, INC. (US) 2012-06-26 US disclosed
US-20120102729-A1 METHOD FOR TREATING ELECTRICAL CABLE AT SUSTAINED ELEVATED PRESSURE NOVINIUM, INC. (US) 2012-05-03 US disclosed
US-7976747-B2 Method for restoring power cables NOVINIUM, INC. (US) 2011-07-12 US disclosed
US-20110009582-A1 Preparation of Activating Supports TOTAL PETROCHEMICALS RESEARCH FELUY (BE) 2011-01-13 US disclosed
US-20100095521-A1 METHOD FOR TREATING ELECTRICAL CABLE AT SUSTAINED ELEVATED PRESSURE NOVINIUM, INC. (US) 2010-04-22 US disclosed
US-7700871-B2 Acid-catalyzed dielectric enhancement fluid and cable restoration method employing same NOVINIUM, INC. (US) 2010-04-20 US disclosed
EP-2170511-A1 PREPARATION OF ACTIVATING SUPPORTS Total Petrochemicals Research Feluy (BE) 2010-04-07 EP disclosed
US-7615247-B2 Promoting transport of dielectric enhancing fluid into polymeric insulation; utilizing residual injection pressure to expand interstitial void volume along entire length of treatment segment NOVINIUM, INC. (US) 2009-11-10 US disclosed
US-7611748-B2 Method for selecting formulations to treat electrical cables NOVINIUM, INC. (US) 2009-11-03 US disclosed
US-20090133799-A1 METHOD FOR RESTORING POWER CABLES NOVINIUM, LLC 2009-05-28 US disclosed
EP-2025403-A1 Preparation of activating supports TOTAL PETROCHEMICALS RESEARCH FELUY (BE) 2009-02-18 EP disclosed
WO-2009013197-A1 PREPARATION OF ACTIVATING SUPPORTS TOTAL PETROCHEMICALS RESEARCH FELUY (BE) 2009-01-29 WO disclosed
US-20080173467-A1 ACID-CATALYZED DIELECTRIC ENHANCEMENT FLUID AND CABLE RESTORATION METHOD EMPLOYING SAME NOVINIUM, INC. (US) 2008-07-24 US disclosed
US-20050192708-A1 Method for selecting formulations to treat electrical cables NOVINIUM, INC. (US) 2005-09-01 US disclosed
US-20050189130-A1 Method for treating electrical cable at sustained elevated pressure NOVINIUM, INC. (US) 2005-09-01 US disclosed