SCHEMBL2989013

SCHEMBL2989013

CC(O)C(=O)c1ccc(O)cc1O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 5/20 0.58
CA1 P00915 5/20 0.58
CA2 P00918 5/20 0.58
CA7 P43166 5/20 0.58
CA9 Q16790 5/20 0.58
CA14 Q9ULX7 5/20 0.58
CES2 O00748 1/20 0.57
MEN1 O00255 4/20 0.55
KMT2A Q03164 4/20 0.55
MAPT P10636 3/20 0.55
CYP3A4 P08684 3/20 0.55
PPARG P37231 1/20 0.55
ALDH1A1 P00352 3/20 0.55
TSHR P16473 1/20 0.55
HSP90AB1 P08238 1/20 0.53
PDK2 Q15119 1/20 0.53
PDK4 Q16654 1/20 0.53
GFER P55789 1/20 0.48
SERPINE1 P05121 1/20 0.47
USP2 O75604 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29378476 0.86 CA12 (0.59) CA12CA1CA2CA7CA9
SCHEMBL1830213 0.86 CA12 (0.59) CA12CA1CA2CA7CA9
SCHEMBL28412793 0.82 CA12 (0.56) CA12CA1CA2CA7CA9
SCHEMBL28412960 0.82 CA12 (0.56) CA12CA1CA2CA7CA9
SCHEMBL9816219 0.81 CA12 (0.54) CA12CA1CA2CA7CA9
SCHEMBL27914486 0.80 CES2 (0.57) CA12CA1CA2CA7CA9
SCHEMBL27884108 0.80 CES2 (0.57) CA12CA1CA2CA7CA9
SCHEMBL10397207 0.79 ALDH1A1 (0.58) CA12CA1CA2CA7CA9
SCHEMBL9407157 0.79 HSP90AB1 (0.58) CA12CA1CA2CA7CA9
SCHEMBL677731 0.79 MEN1 (0.77) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110240582-A A kind of chromocor derivative and the preparation method and application thereof with inhibition tumour cell 贵州省中国科学院天然产物化学重点实验室(贵州医科大学天然产物化学重点实验室) 2019-09-17 CN claimed
US-20080255228-A1 Ascorbic Acid Complexes for Skin Care Including Treatment of Dark Skin & Wrinkles BIODERM RESEARCH (US) 2008-10-16 US claimed
US-20080254130-A1 Skin Antiaging & Brightening via Multi-function Treatment of Enzyme Dysfunction BIODERM RESEARCH (US) 2008-10-16 US claimed
US-7427690-B2 Multifunction “crown complexes” from amino acids and peptides for skin and hair restoration BIODERM RESEARCH (US) 2008-09-23 US claimed
US-20070099886-A1 Multifunction \"Crown Complexes\" from Amino Acids and Peptides for Skin and Hair Restoration BIODERM RESEARCH (US) 2007-05-03 US claimed
US-20060074108-A1 Matrix metalloprotease (MMP) inhibitors and their application in cosmetic and pharmaceutical composition BIODERM RESEARCH (US) 2006-04-06 US claimed
US-20050271608-A1 Skin whitening compositions based on hydroxyaryl alkyl ketones and their isosteric derivatives GUPTA SHYAM K 2005-12-08 US claimed
CN-112888498-A Composition useful for producing acid gas separation membranes 住友化学株式会社 2021-06-01 CN disclosed
CN-110240582-A A kind of chromocor derivative and the preparation method and application thereof with inhibition tumour cell 贵州省中国科学院天然产物化学重点实验室(贵州医科大学天然产物化学重点实验室) 2019-09-17 CN disclosed
US-8227426-B2 Chiral complexes of ascorbic acid with natural antioxidant and anti-inflammatory ketones including aloe, citrus, ginger, and mango for skin and hair care ISLAND KINETICS INC. (US) 2012-07-24 US disclosed
US-20110059907-A1 Chiral Complexes of Ascorbic Acid with Natural Antioxidant and Anti-Inflammatory Ketones Including Aloe, Citrus, Ginger, and Mango for Skin and Hair Care ISLAND KINETICS INC. (US) 2011-03-10 US disclosed
US-7834210-B2 Hair loss prevention by natural amino acid and peptide complexes BIODERM RESEARCH (US) 2010-11-16 US disclosed
US-7777073-B2 Topical delivery system for antiaging and skin whitening agents BIODERM RESEARCH (US) 2010-08-17 US disclosed
US-20080139507-A1 Method of Treating Skin Condition Including Acne, Skin Aging, Body Odor & Diaper Rash by Zinc Zeolite Clathrates BIODERM RESEARCH (US) 2008-06-12 US disclosed
US-20070099886-A1 Multifunction \"Crown Complexes\" from Amino Acids and Peptides for Skin and Hair Restoration BIODERM RESEARCH (US) 2007-05-03 US disclosed
WO-2003082976-A1 THERMOSETTING RESIN COMPOSITION AND EPOXY RESIN MOLDING MATERIAL USING THE COMPOSITION AND SEMICONDUCTOR DEVICE SUMITOMO BAKELITE COMPANY LIMITED (JP) 2003-10-09 WO disclosed
US-6087502-A COMPOUNDS FOR MARKING ANTIGENS OR ANTIBODIES RECEPTOR BINDING ASSAY MOCHIDA PHARMACEUTICALS CO., LTD. (JP) 2000-07-11 US disclosed
EP-0761652-A1 Acridinium compound having a plurality of luminescent groups and binding groups, and conjugate thereof MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 1997-03-12 EP disclosed
US-3998782-A AGAINST HEAT AKZO N.V. (NL) 1976-12-21 US disclosed
US-3985783-A Process for ring acylation of phenols THE DOW CHEMICAL COMPANY (US) 1976-10-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110059907-A1 Chiral Complexes of Ascorbic Acid with Natural Antioxidant and Anti-Inflammatory Ketones Including Aloe, Citrus, Ginger, and Mango for Skin and Hair Care GLA, LPO, PLOD3 CA12 2732/4885CA1 2906/4885CA2 1234/4885
US-20080254130-A1 Skin Antiaging & Brightening via Multi-function Treatment of Enzyme Dysfunction PSMB1, PLOD3, CUTA CA12 4776/4885CA1 4867/4885CA2 4627/4885
US-20080255228-A1 Ascorbic Acid Complexes for Skin Care Including Treatment of Dark Skin & Wrinkles PROC, COL1A1, CUTA CA12 4408/4885CA1 4577/4885CA2 1976/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.