SCHEMBL9407183

SCHEMBL9407183

CCCCCCOc1cc(F)c(C(=O)O)c(F)c1F

nearest known ligand 0.52

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 2/20 0.48
PLA2G2A P14555 1/20 0.48
ALDH1A1 P00352 1/20 0.46
HPGD P15428 1/20 0.46
PLA2G2D Q9UNK4 1/20 0.45
PTPN11 Q06124 4/20 0.45
S1PR3 Q99500 1/20 0.45
THRA P10827 1/20 0.44
THRB P10828 1/20 0.44
TP53 P04637 1/20 0.44
TSHR P16473 1/20 0.44
PLA2G4B P0C869 1/20 0.43
PTPN6 P29350 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14261945 0.86 SMPD1 (0.43) PTPN1S1PR3THRATHRB
SCHEMBL1583340 0.80 PLA2G2A (0.64) PLA2G2APTPN11THRATHRBTP53
SCHEMBL8640999 0.80 PLA2G2A (0.64) PLA2G2APTPN11THRATHRBTP53
SCHEMBL4779665 0.78 THRA (0.50) PTPN1PLA2G2ATHRATHRBTP53
SCHEMBL1582848 0.78 THRA (0.50) PTPN1PLA2G2ATHRATHRBTP53
SCHEMBL1583014 0.78 THRA (0.50) PTPN1PLA2G2ATHRATHRBTP53
SCHEMBL1582944 0.78 THRA (0.50) PTPN1PLA2G2ATHRATHRBTP53
SCHEMBL1583240 0.78 THRA (0.50) PTPN1PLA2G2ATHRATHRBTP53
SCHEMBL18523517 0.77 RARB (0.40) PTPN1PLA2G2ATP53TSHR
SCHEMBL14261997 0.75 L3MBTL1 (0.40) S1PR3THRATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0603786-A2 Alkyl-substituted hydroquinone derivatives for use in ferro-electric liquid crystal mixtures HOECHST AKTIENGESELLSCHAFT (DE) 1994-06-29 EP disclosed