SCHEMBL9407394

SCHEMBL9407394

CC(C)(C)C(=O)OC[C@@H]1CC[C@@H](n2cnc3c(N)ncnc32)O1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCHE P06276 1/20 0.55
STING1 Q86WV6 6/20 0.49
ADA P00813 1/20 0.47
HSP90B1 P14625 1/20 0.47
TP53 P04637 1/20 0.47
CYP2C9 P11712 1/20 0.47
NFKB1 P19838 1/20 0.47
MAPK1 P28482 1/20 0.47
HSD17B10 Q99714 1/20 0.47
MEN1 O00255 1/20 0.47
ALDH1A1 P00352 1/20 0.47
APEX1 P27695 1/20 0.47
PI4KA P42356 1/20 0.47
BLM P54132 1/20 0.47
KMT2A Q03164 1/20 0.47
ADCY1 Q08828 1/20 0.47
PI4K2B Q8TCG2 1/20 0.47
PI4K2A Q9BTU6 1/20 0.47
PI4KB Q9UBF8 1/20 0.47
ADORA3 P0DMS8 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9407393 1.00 BCHE (0.55) BCHESTING1ADAHSP90B1TP53
SCHEMBL6243153 0.89 BCHE (0.55) BCHEADAHSP90B1TP53CYP2C9
SCHEMBL21427226 0.89 BCHE (0.55) BCHEADAHSP90B1TP53CYP2C9
SCHEMBL21539918 0.86 STING1 (0.47) BCHESTING1ALDH1A1
SCHEMBL9371177 0.85 BCHE (0.52) BCHEADAHSP90B1TP53CYP2C9
SCHEMBL14615380 0.83 STING1 (0.53) STING1HSP90B1ADORA3ADORA2BAHCY
SCHEMBL9588917 0.83 ADORA3 (0.44) BCHEMAPK1ALDH1A1ADORA3ADORA2B
SCHEMBL23516968 0.83 BCHE (0.57) BCHEADATP53CYP2C9NFKB1
SCHEMBL20624631 0.83 BCHE (0.57) BCHEADATP53CYP2C9NFKB1
SCHEMBL22524135 0.83 BCHE (0.57) BCHEADATP53CYP2C9NFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0598910-A1 PROCESS FOR PRODUCING NUCLEOSIDE DERIVATIVE Japan Tobacco Inc. (JP) 1994-06-01 EP disclosed