Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 6/20 | 0.53 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.49 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.49 |
| ▸ | AHCY | P23526 | 6/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9407394 | 0.83 | BCHE (0.55) | STING1HSP90B1ADORA3ADORA2BAHCY | |
| SCHEMBL9407393 | 0.83 | BCHE (0.55) | STING1HSP90B1ADORA3ADORA2BAHCY | |
| SCHEMBL12154782 | 0.83 | AHCY (0.47) | HSP90B1ADORA3ADORA2BAHCY | |
| SCHEMBL12154573 | 0.82 | ADORA3 (0.59) | ADORA3ADORA2BAHCY | |
| SCHEMBL20324814 | 0.82 | P2RY1 (0.66) | — | |
| SCHEMBL11584944 | 0.81 | ADORA1 (0.67) | ADORA3ADORA2B | |
| SCHEMBL23348998 | 0.80 | MARS1 (0.45) | STING1HSP90B1ADORA3ADORA2BAHCY | |
| SCHEMBL4625882 | 0.80 | POLB (0.62) | STING1HSP90B1 | |
| SCHEMBL20059156 | 0.79 | DOT1L (0.44) | STING1HSP90B1ADORA3ADORA2BAHCY | |
| SCHEMBL8970318 | 0.79 | NT5E (0.65) | STING1ADORA3ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007021610-A2 | RIBONUCLEOSIDE CYCLIC ACETAL DERIVATIVES FOR THE TREATMENT OF RNA-DEPENDENT RNA VIRAL INFECTION | MERCK & CO., INC. (US) | 2007-02-22 | — | — | WO | disclosed |