Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 11/20 | 0.49 |
| ▸ | CHEK2 | O96017 | 3/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.46 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.46 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9408111 | 0.80 | TDP1 (0.47) | CHEK2 | |
| SCHEMBL22365321 | 0.77 | SLC2A1 (0.61) | GPR119CHEK2HDAC1SLC2A1 | |
| SCHEMBL7372387 | 0.77 | ITGB3 (0.57) | GPR119CHEK2HDAC1 | |
| SCHEMBL7835824 | 0.75 | MIF (0.61) | GPR119CHEK2HDAC1 | |
| SCHEMBL15539074 | 0.75 | GPR119 (0.57) | GPR119CHEK2HDAC1 | |
| SCHEMBL18842715 | 0.75 | GPR119 (0.57) | GPR119CHEK2HDAC1 | |
| SCHEMBL391486 | 0.75 | GPR119 (0.51) | GPR119SLC2A1ACKR3 | |
| SCHEMBL15540227 | 0.75 | CHEK2 (0.53) | GPR119CHEK2HDAC1SLC2A1 | |
| SCHEMBL7322943 | 0.74 | GPR119 (0.66) | GPR119 | |
| SCHEMBL241130 | 0.74 | GPR119 (0.59) | GPR119CHEK2HDAC1SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0608858-A1 | 5-Membered heterocycles as aggregation inhibitors | Dr. Karl Thomae GmbH (DE) | 1994-08-03 | — | — | EP | disclosed |