Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.44 |
| ▸ | JAK2 | O60674 | 5/20 | 0.43 |
| ▸ | JAK3 | P52333 | 5/20 | 0.43 |
| ▸ | PTK2 | Q05397 | 5/20 | 0.43 |
| ▸ | WNT3A | P56704 | 1/20 | 0.42 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.42 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
| ▸ | IGF1R | P08069 | 1/20 | 0.40 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9408156 | 1.00 | GPR119 (0.47) | GPR119NAMPTPTPN2PTPN1PTPN6 | |
| SCHEMBL9407954 | 0.90 | GPR119 (0.45) | GPR119NAMPTPTPN2PTPN1PTPN6 | |
| SCHEMBL9407986 | 0.88 | GPR119 (0.47) | GPR119NAMPTPTPN2PTPN1PTPN6 | |
| SCHEMBL6538550 | 0.84 | GPR119 (0.55) | GPR119PTPN2PTPN1PTPN6HTT | |
| SCHEMBL9408006 | 0.82 | GPR119 (0.53) | GPR119NAMPTPTPN2PTPN1PTPN6 | |
| SCHEMBL9407972 | 0.80 | DGAT1 (0.41) | P2RY14 | |
| SCHEMBL9407975 | 0.80 | DGAT1 (0.41) | P2RY14 | |
| Hydrochloric Acid SCHEMBL9408043 | 0.79 | DGAT1 (0.41) | P2RY14 | |
| Hydrochloric Acid SCHEMBL9408112 | 0.79 | DGAT1 (0.41) | P2RY14 | |
| SCHEMBL9408057 | 0.79 | GPR119 (0.52) | GPR119NAMPTPTPN2PTPN1PTPN6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0608858-A1 | 5-Membered heterocycles as aggregation inhibitors | Dr. Karl Thomae GmbH (DE) | 1994-08-03 | — | — | EP | disclosed |