SCHEMBL940804

SCHEMBL940804

C[CH][Si](C)(C)c1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.45
ESR1 P03372 1/20 0.41
ESR2 Q92731 1/20 0.41
NR1H2 P55055 2/20 0.33
NR1H3 Q13133 2/20 0.33
ALOX12 P18054 2/20 0.32
LMNA P02545 1/20 0.32
TSHR P16473 1/20 0.32
ACHE P22303 1/20 0.32
MGAM O43451 1/20 0.31
CYP2A6 P11509 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9773554 0.80 ESR1 (0.42) MAPTESR1ESR2NR1H2NR1H3
SCHEMBL9773556 0.80 ESR1 (0.42) MAPTESR1ESR2NR1H2NR1H3
SCHEMBL9773562 0.80 ESR1 (0.42) MAPTESR1ESR2NR1H2NR1H3
SCHEMBL7898055 0.79 MAPT (0.38) MAPTESR1ESR2NR1H2NR1H3
SCHEMBL7898054 0.79 MAPT (0.38) MAPTESR1ESR2NR1H2NR1H3
SCHEMBL453982 0.76 NR1H2 (0.48) MAPTESR1ESR2NR1H2NR1H3
SCHEMBL2595602 0.74 MAPT (0.38) MAPTESR1ESR2NR1H2NR1H3
SCHEMBL2971870 0.72 MAPT (0.37) MAPTESR1ESR2NR1H2NR1H3
SCHEMBL5779325 0.72 ESR1 (0.37) MAPTESR1ESR2NR1H2NR1H3
SCHEMBL4530855 0.72 NR1H2 (0.46) MAPTESR1ESR2NR1H2NR1H3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3848399-B1 TRANSITION METAL COMPOUND AND METHOD FOR PRODUCING OLEFIN POLYMER IDEMITSU KOSAN CO (JP) 2024-07-10 EP disclosed
US-11795188-B2 Transition metal compound and method for producing olefin polymer IDEMITSU KOSAN CO., LTD. (JP) 2023-10-24 US disclosed
US-20230235202-A1 PLASTICIZER FOR RESINS IDEMITSU KOSAN CO.,LTD. (JP) 2023-07-27 US disclosed
EP-3848399-A1 TRANSITION METAL COMPOUND AND METHOD FOR PRODUCING OLEFIN POLYMER Idemitsu Kosan Co., Ltd. (JP) 2021-07-14 EP disclosed
US-20210198300-A1 TRANSITION METAL COMPOUND AND METHOD FOR PRODUCING OLEFIN POLYMER IDEMITSU KOSAN CO.,LTD. (JP) 2021-07-01 US disclosed
EP-2915858-B1 ADHESIVE COMPOSITION AND ADHESIVE TAPE USING SAME IDEMITSU KOSAN CO (JP) 2020-12-02 EP disclosed
EP-3006535-B1 BASE POLYMER FOR HOT-MELT ADHESIVE, AND HOT-MELT ADHESIVE IDEMITSU KOSAN CO (JP) 2020-02-05 EP disclosed
EP-2915825-B1 POLYOLEFIN, ADHESIVE COMPOSITION CONTAINING SAME, AND ADHESIVE TAPE USING SAID ADHESIVE COMPOSITION IDEMITSU KOSAN CO (JP) 2019-06-26 EP disclosed
US-10066131-B2 Hot-melt adhesive for woodworking IDEMITSU KOSAN CO., LTD. (JP) 2018-09-04 US disclosed
US-20170355888-A1 HOT-MELT ADHESIVE FOR WOODWORKING IDEMITSU KOSAN CO., LTD. (JP) 2017-12-14 US disclosed
US-20030017940-A1 Transition metal compound, polymerization catalysts for olefin , olefin polymers and process for their production IDEMITSU KOSAN CO. LTD. (JP) 2003-01-23 US disclosed
US-20020193536-A1 Transition metal compound, polymerization catalysts for olefins, olefin polymers and process for their production IDEMITSU KOSAN CO. LTD. (JP) 2002-12-19 US disclosed
EP-1247814-A1 TRANSITION METAL COMPOUNDS, POLYMERIZATION CATALYSTS FOR OLEFINS, OLEFIN POLYMERS AND PROCESS FOR THEIR PRODUCTION IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2002-10-09 EP disclosed
EP-1231226-A1 ROLLED POLYPROPYLENE AND INJECTION-MOLDED POLYPROPYLENE IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2002-08-14 EP disclosed
EP-1227112-A1 PROPYLENE POLYMERS AND RESIN COMPOSITION AND MOLDING CONTAINING THE POLYMERS IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2002-07-31 EP disclosed
US-5889012-A INSECTICIDE, ACARICIDES, FUNGICIDES HOECHST-SCHERING AGREVO GMBH (DE) 1999-03-30 US disclosed
EP-0714393-B1 THIAZOLES AS ANTIVIRAL PFIZER (US) 1998-09-23 EP disclosed
US-5789408-A Antiviral thiazoles PFIZER INC. (US) 1998-08-04 US disclosed
EP-0714393-A1 THIAZOLES AS ANTIVIRAL PFIZER INC. (US) 1996-06-05 EP disclosed
WO-1995005378-A1 ANTIVIRAL THIAZOLES PFIZER INC. (US) 1995-02-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210198300-A1 TRANSITION METAL COMPOUND AND METHOD FOR PRODUCING OLEFIN POLYMER H1-0, C9, C5 MAPT 4097/4885ESR1 105/4885ESR2 285/4885
US-20020193536-A1 Transition metal compound, polymerization catalysts for olefins, olefin polymers and process for their production CCNE2, PYM1, AP1M1 MAPT 2296/4885ESR1 2312/4885ESR2 2198/4885
US-11795188-B2 Transition metal compound and method for producing olefin polymer H1-0, C9, C5 MAPT 4097/4885ESR1 105/4885ESR2 285/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.