Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.30 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.30 |
| ▸ | AHR | P35869 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31054141 | 0.78 | MAPT (0.35) | MAPTESR1ESR2LMNATSHR | |
| SCHEMBL940804 | 0.74 | MAPT (0.45) | MAPTESR1ESR2LMNATSHR | |
| SCHEMBL28545159 | 0.71 | ALDH1A1 (0.42) | MAPTESR1ESR2LMNATSHR | |
| SCHEMBL226240 | 0.71 | ALDH1A1 (0.41) | ESR1ESR2TSHRALDH1A1KDM4E | |
| SCHEMBL4625993 | 0.70 | TP53 (0.36) | MAPTESR1ESR2LMNATSHR | |
| SCHEMBL8543835 | 0.70 | MAPT (0.38) | MAPTESR1ESR2LMNAALDH1A1 | |
| SCHEMBL8549786 | 0.69 | MAPT (0.33) | MAPTESR1ESR2TSHRALDH1A1 | |
| SCHEMBL6550222 | 0.67 | MAPT (0.36) | MAPTESR1ESR2 | |
| SCHEMBL28638586 | 0.67 | MAPT (0.35) | MAPTESR1ESR2LMNATSHR | |
| SCHEMBL8002913 | 0.67 | ALDH1A1 (0.32) | ESR1ESR2TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100323000-A1 | METHOD AND PROCESS FOR PREPARING CARDIOLIPIN | NEOPHARM, INC. (US) | 2010-12-23 | — | — | US | claimed |
| US-6953850-B1 | Protecting groups for carbohydrate synthesis | ALCHEMIA PTY. LTD. (AU) | 2005-10-11 | — | — | US | claimed |
| US-11814484-B2 | Modified filler particles and silicone compositions comprising the same | MOMENTIVE PERFORMANCE MATERIALS GMBH | 2023-11-14 | — | — | US | disclosed |
| CN-108026372-B | Modified filler particles and silicone compositions containing the same | 莫门蒂夫性能材料有限公司 | 2022-03-15 | — | — | CN | disclosed |
| US-20220002492-A1 | MODIFIED FILLER PARTICLES AND SILICONE COMPOSITIONS COMPRISING THE SAME | MOMENTIVE PERFORMANCE MATERIALS GMBH (DE) | 2022-01-06 | — | — | US | disclosed |
| US-11015024-B2 | Modified filler particles and silicone compositions comprising the same | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2021-05-25 | — | — | US | disclosed |
| US-20180208718-A1 | MODIFIED FILLER PARTICLES AND SILICONE COMPOSITIONS COMPRISING THE SAME | MOMENTIVE PERFORMANCE MATERIALS INC. | 2018-07-26 | — | — | US | disclosed |
| EP-3325557-A1 | MODIFIED FILLER PARTICLES AND SILICONE COMPOSITIONS COMPRISING THE SAME | Momentive Performance Materials GmbH (DE) | 2018-05-30 | — | — | EP | disclosed |
| WO-2017012715-A1 | MODIFIED FILLER PARTICLES AND SILICONE COMPOSITIONS COMPRISING THE SAME | MOMENTIVE PERFORMANCE MATERIALS GMBH (DE) | 2017-01-26 | — | — | WO | disclosed |
| EP-2601204-A2 | MODIFIED NUCLEOSIDES AND OLIGOMERIC COMPOUNDS PREPARED THEREFROM | Isis Pharmaceuticals, Inc. (US) | 2013-06-12 | — | — | EP | disclosed |
| WO-2011139702-A2 | MODIFIED NUCLEOSIDES AND OLIGOMERIC COMPOUNDS PREPARED THEREFROM | ISIS PHARMACEUTICALS, INC. (US) | 2011-11-10 | — | — | WO | disclosed |
| EP-0592534-A4 | SILYL PHOSPHORYLATING REAGENTS AND METHODS OF USING THEM | ABBOTT LAB (US) | 1994-07-06 | — | — | EP | disclosed |
| EP-0592534-A1 | SILYL PHOSPHORYLATING REAGENTS AND METHODS OF USING THEM | ABBOTT LABORATORIES (US) | 1994-04-20 | — | — | EP | disclosed |
| EP-0591344-A1 | A PROCESS FOR SYNTHESIS OF SILYL ALCOHOLS | ABBOTT LABORATORIES (US) | 1994-04-13 | — | — | EP | disclosed |
| EP-0591302-A1 | SUBSTITUTED SILYL ALCOHOLS | ABBOTT LABORATORIES (US) | 1994-04-13 | — | — | EP | disclosed |
| WO-1992022561-A1 | A PROCESS FOR SYNTHESIS OF SILYL ALCOHOLS | ABBOTT LABORATORIES (US) | 1992-12-23 | — | — | WO | disclosed |
| WO-1992022557-A1 | SUBSTITUTED SILYL ALCOHOLS | ABBOTT LABORATORIES (US) | 1992-12-23 | — | — | WO | disclosed |
| WO-1992021689-A1 | SILYL PHOSPHORYLATING REAGENTS AND METHODS OF USING THEM | ABBOTT LABORATORIES (US) | 1992-12-10 | — | — | WO | disclosed |
| US-5159095-A | Reagant for phosphorylating oligonucleotides | ABBOTT LABORATORIES (US) | 1992-10-27 | — | — | US | disclosed |
| US-5113005-A | Hydrosilation | ABBOTT LABORATORIES (US) | 1992-05-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100323000-A1 | METHOD AND PROCESS FOR PREPARING CARDIOLIPIN | PHOSPHO1, SGMS1, SGMS2 | MAPT 4674/4885ESR1 4835/4885ESR2 4861/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.