Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 12/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 11/20 | 0.47 |
| ▸ | DRD2 | P14416 | 9/20 | 0.47 |
| ▸ | HTR1A | P08908 | 3/20 | 0.47 |
| ▸ | HTR2C | P28335 | 2/20 | 0.47 |
| ▸ | HRH1 | P35367 | 2/20 | 0.47 |
| ▸ | DRD3 | P35462 | 2/20 | 0.47 |
| ▸ | HTR6 | P50406 | 2/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | DRD1 | P21728 | 1/20 | 0.46 |
| ▸ | HTR7 | P34969 | 9/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8916604 | 0.84 | HTR6 (0.64) | HTR2AKCNH2DRD2HTR1AHTR2C | |
| SCHEMBL1545800 | 0.72 | DRD2 (0.64) | HTR2AKCNH2DRD2HTR7SLC6A4 | |
| SCHEMBL8916506 | 0.71 | ACHE (0.52) | HTR2AKCNH2DRD2HTR1AHTR2C | |
| SCHEMBL8347543 | 0.71 | DRD2 (0.64) | HTR2AKCNH2DRD2HTR7SLC6A4 | |
| SCHEMBL13898738 | 0.71 | DRD2 (0.67) | HTR2AKCNH2DRD2HTR7SLC6A4 | |
| Hydrochloric Acid SCHEMBL8911231 | 0.71 | DRD2 (0.61) | HTR2AKCNH2DRD2HTR7SLC6A4 | |
| Hydrochloric Acid SCHEMBL8911228 | 0.71 | DRD2 (0.61) | HTR2AKCNH2DRD2HTR7SLC6A4 | |
| Hydrochloric Acid SCHEMBL8480127 | 0.70 | DRD2 (0.60) | HTR2AKCNH2DRD2HTR7SLC6A4 | |
| SCHEMBL8917083 | 0.70 | ACHE (0.50) | HTR2AKCNH2DRD2HTR1AHTR2C | |
| SCHEMBL8918221 | 0.70 | ACHE (0.50) | HTR2AKCNH2DRD2HTR1AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0596125-A1 | CONDENSED THIOPHENE COMPOUND AND PHARMACEUTICAL USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1994-05-11 | — | — | EP | disclosed |