SCHEMBL940832

SCHEMBL940832

CCC(P)c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.52
HTR2A P28223 4/20 0.46
HRH1 P35367 3/20 0.46
TDP1 Q9NUW8 1/20 0.44
AOC3 Q16853 3/20 0.44
CCR5 P51681 1/20 0.43
MIF P14174 1/20 0.42
TAAR1 Q96RJ0 3/20 0.41
HKDC1 Q2TB90 1/20 0.41
TRPA1 O75762 1/20 0.41
NOS3 P29474 1/20 0.39
NOS2 P35228 1/20 0.39
POLB P06746 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL9619421 0.97 LMNA (0.50) LMNAHTR2AHRH1TDP1AOC3
SCHEMBL9619448 0.80 AOC3 (0.47) LMNAHTR2AHRH1TDP1AOC3
Hydrochloric Acid SCHEMBL9619310 0.78 AOC3 (0.46) LMNAHTR2AHRH1TDP1AOC3
SCHEMBL13754798 0.78 HTR2A (0.44) LMNAHTR2AHRH1TDP1TAAR1
SCHEMBL21579065 0.77 CHRNA7 (0.46) LMNATDP1
SCHEMBL14043185 0.77 IDO1 (0.40) LMNATDP1NOS3NOS2
SCHEMBL28904482 0.75 TSHR (0.50) LMNATDP1TAAR1
SCHEMBL54346 0.75 HTR2A (0.59) LMNAHTR2AHRH1TDP1MIF
Trimethylammonium SCHEMBL27512056 0.74 HTR2A (0.65) LMNAHTR2AHRH1TDP1AOC3
SCHEMBL27633716 0.74 TRPA1 (0.45) LMNAHTR2AHRH1TDP1AOC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 112 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0774514-B1 A method for quantitatively determining creatine kinase and a reagent therefor KYOWA MEDEX CO LTD (JP) 2000-03-08 EP claimed
EP-3848399-B1 TRANSITION METAL COMPOUND AND METHOD FOR PRODUCING OLEFIN POLYMER IDEMITSU KOSAN CO (JP) 2024-07-10 EP disclosed
US-11795188-B2 Transition metal compound and method for producing olefin polymer IDEMITSU KOSAN CO., LTD. (JP) 2023-10-24 US disclosed
US-20230235202-A1 PLASTICIZER FOR RESINS IDEMITSU KOSAN CO.,LTD. (JP) 2023-07-27 US disclosed
US-20230001616-A1 LAYERED BODY AND EXTRUSION-MOLDED ARTICLE DAIKIN INDUSTRIES, LTD. (JP) 2023-01-05 US disclosed
CN-111517902-B Aerobic oxidation system containing sulfinic acid, sulfonic acid or derivatives thereof and photo-oxidation promoting method thereof 清华大学 2022-06-14 CN disclosed
US-11246862-B2 Process for the preparation of lifitegrast MANKIND PHARMA LTD. (IN) 2022-02-15 US disclosed
EP-3848399-A1 TRANSITION METAL COMPOUND AND METHOD FOR PRODUCING OLEFIN POLYMER Idemitsu Kosan Co., Ltd. (JP) 2021-07-14 EP disclosed
US-20210198300-A1 TRANSITION METAL COMPOUND AND METHOD FOR PRODUCING OLEFIN POLYMER IDEMITSU KOSAN CO.,LTD. (JP) 2021-07-01 US disclosed
EP-2478981-B1 SILVER-(CONJUGATED COMPOUND) COMPLEX SUMITOMO CHEMICAL CO (JP) 2020-12-23 EP disclosed
US-20050043495-A1 Propylene polymer and composition containing the same, molded object and laminate comprising these, and processes for producing propylene polymer and composition containing the same IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2005-02-24 US disclosed
US-6770772-B2 DOUBLE CROSS-LINKED METALLOCENE COMPLEX; HIGH MOLECULAR WEIGHT, STEREOSPECIFIC; NARROW MOLECULAR WEIGHT DISTRIBUTION IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2004-08-03 US disclosed
US-6770355-B1 USABLE AS A SUBSTITUTE FOR SOFT VINYL CHLORIDE FILMS IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2004-08-03 US disclosed
US-6734270-B1 Polypropylene-based calendered article and injection-molded article IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2004-05-11 US disclosed
US-20030017940-A1 Transition metal compound, polymerization catalysts for olefin , olefin polymers and process for their production IDEMITSU KOSAN CO. LTD. (JP) 2003-01-23 US disclosed
EP-1247814-A1 TRANSITION METAL COMPOUNDS, POLYMERIZATION CATALYSTS FOR OLEFINS, OLEFIN POLYMERS AND PROCESS FOR THEIR PRODUCTION IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2002-10-09 EP disclosed
EP-1241206-A1 POLYPROPYLENE FILM AND MULTILAYERED LAMINATE IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2002-09-18 EP disclosed
EP-1231236-A1 POLYPROPYLENE FILM AND MULTILAYERED LAMINATE IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2002-08-14 EP disclosed
EP-1231226-A1 ROLLED POLYPROPYLENE AND INJECTION-MOLDED POLYPROPYLENE IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2002-08-14 EP disclosed
EP-1095951-A1 PROPYLENE POLYMER AND COMPOSITION CONTAINING THE SAME, MOLDED OBJECT AND LAMINATE COMPRISING THESE, AND PROCESSES FOR PRODUCING PROPYLENE POLYMER AND COMPOSITION CONTAINING THE SAME IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2001-05-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11246862-B2 Process for the preparation of lifitegrast LIFR, PTGFR, CSF1R LMNA 1303/4885HTR2A 2392/4885HRH1 2187/4885
US-20210198300-A1 TRANSITION METAL COMPOUND AND METHOD FOR PRODUCING OLEFIN POLYMER H1-0, C9, C5 LMNA 1550/4885HTR2A 3904/4885HRH1 745/4885
US-11795188-B2 Transition metal compound and method for producing olefin polymer H1-0, C9, C5 LMNA 1550/4885HTR2A 3904/4885HRH1 745/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.