SCHEMBL27633716

SCHEMBL27633716

OCC(P)c1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 4/20 0.45
KDM4E B2RXH2 2/20 0.41
ALDH1A1 P00352 1/20 0.41
HTR2A P28223 3/20 0.41
HRH1 P35367 2/20 0.41
LMNA P02545 1/20 0.41
TAAR1 Q96RJ0 1/20 0.40
GSR P00390 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
AOC3 Q16853 2/20 0.39
CYP2D6 P10635 1/20 0.39
SRC P12931 1/20 0.39
RIPK1 Q13546 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13754798 0.78 HTR2A (0.44) HTR2AHRH1LMNATAAR1TDP1
SCHEMBL193835 0.75 HTR2A (0.52) TRPA1KDM4EHTR2AHRH1LMNA
SCHEMBL940832 0.74 LMNA (0.52) TRPA1HTR2AHRH1LMNATAAR1
SCHEMBL148756 0.72 TRPA1 (0.48) TRPA1KDM4EHTR2ALMNATAAR1
SCHEMBL11744344 0.72 SLC6A2 (0.50) TRPA1KDM4EHTR2ALMNATAAR1
Hydrochloric Acid SCHEMBL6251948 0.72 HTR2A (0.50) TRPA1KDM4EHTR2AHRH1LMNA
Ammonia Solution, Strong SCHEMBL28352255 0.72 HTR2A (0.50) TRPA1KDM4EHTR2AHRH1LMNA
SCHEMBL995480 0.72 SLC6A2 (0.48) TRPA1KDM4EALDH1A1LMNATAAR1
Bromide SCHEMBL27815898 0.72 HTR2A (0.39) HTR2AHRH1LMNATAAR1TDP1
SCHEMBL197336 0.72 SLC6A2 (0.48) HTR2ATAAR1CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1686972-A Cross couple method for synthesizing compound of liquid crystal from 2-2 phenyl phosphine ethanol through palladium catalysis UNIV DALIAN TECH (CN) 2005-10-26 CN disclosed