SCHEMBL9408481

SCHEMBL9408481

CCOC(=O)C(C)(F)C(=O)Nc1nc(OC)cc(OC)n1

nearest known ligand 0.50

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.50
ALDH1A1 P00352 4/20 0.44
MAPT P10636 3/20 0.44
KDM4E B2RXH2 1/20 0.44
AR P10275 2/20 0.41
TP53 P04637 1/20 0.41
GLA P06280 1/20 0.41
GAA P10253 1/20 0.40
LMNA P02545 1/20 0.40
HTT P42858 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
KMT2A Q03164 1/20 0.39
TSHR P16473 1/20 0.37
POLB P06746 1/20 0.37
MMP8 P22894 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8538892 0.77 CYP1A2 (0.62) CYP1A2ALDH1A1MAPTKDM4ETP53
SCHEMBL3791688 0.71 CYP1A2 (0.72) CYP1A2ALDH1A1MAPTKDM4ETP53
SCHEMBL9740893 0.71 CYP1A2 (0.57) CYP1A2ALDH1A1MAPTKDM4ETP53
SCHEMBL2984390 0.70 MAPT (0.59) CYP1A2ALDH1A1MAPTKDM4ETP53
SCHEMBL9763452 0.70 CYP1A2 (0.53) CYP1A2ALDH1A1MAPTKDM4ETP53
SCHEMBL8976238 0.70 ALDH1A1 (0.38) CYP1A2ALDH1A1MAPTKDM4EAR
SCHEMBL27583049 0.70 CYP1A2 (0.60) CYP1A2ALDH1A1MAPTKDM4ETP53
SCHEMBL8431787 0.69 CYP1A2 (0.75) CYP1A2ALDH1A1MAPTKDM4ETP53
Benzene SCHEMBL10687864 0.69 ALDH1A1 (0.53) CYP1A2ALDH1A1MAPTKDM4ETP53
SCHEMBL2702801 0.68 CYP1A2 (0.72) CYP1A2ALDH1A1MAPTKDM4ETP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-6298742-A None JP disclosed
JP-H06298742-A FLUORINATED PYRIMIDINAMIDE DERIVATIVE AND HERBICIDE CONTAINING THE SAME AS ACTIVE INGREDIENT MITSUBISHI PETROCHEM CO LTD 1994-10-25 JP disclosed