Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9408730 | 0.88 | ADRB2 (0.43) | LMNAALDH1A1TDP1MAPTADRB2 | |
| SCHEMBL9408657 | 0.80 | ALDH1A1 (0.36) | ALDH1A1MAPTRAB9AL3MBTL1 | |
| SCHEMBL9408706 | 0.79 | ALDH1A1 (0.39) | ALDH1A1 | |
| SCHEMBL9408731 | 0.76 | ADRB2 (0.43) | ALDH1A1MAPK1KMT2AMAPTADRB2 | |
| SCHEMBL9408919 | 0.72 | MAPT (0.39) | LMNAALDH1A1TDP1MAPTTSHR | |
| SCHEMBL29012462 | 0.71 | ALDH1A1 (0.51) | LMNAALDH1A1ALOX15APEX1MAPK1 | |
| SCHEMBL9408734 | 0.71 | MAPT (0.46) | LMNAALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL9408597 | 0.71 | MAPT (0.46) | LMNAALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL9385181 | 0.71 | MAPT (0.34) | LMNAALDH1A1ALOX15APEX1MAPK1 | |
| SCHEMBL9408686 | 0.70 | TSHR (0.43) | ALDH1A1CA2ADRB2ADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0593998-A1 | Pyrimidinylthioalkane herbicides | NIHON BAYER AGROCHEM K.K. (JP) | 1994-04-27 | — | — | EP | disclosed |