Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | FNTA | P49354 | 1/20 | 0.45 |
| ▸ | FNTB | P49356 | 1/20 | 0.45 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8523377 | 0.96 | THRB (0.49) | THRBFNTAFNTBPGGT1BLMNA | |
| SCHEMBL9408920 | 0.90 | PDE4B (0.49) | LMNAMAPTRAB9APDE4BHDAC1 | |
| SCHEMBL25303952 | 0.81 | NR1I2 (0.54) | THRBFNTAFNTBPGGT1BLMNA | |
| SCHEMBL303214 | 0.81 | NR1I2 (0.54) | THRBFNTAFNTBPGGT1BLMNA | |
| SCHEMBL7119167 | 0.79 | HPGD (0.47) | HPGDTP53TSHRPDE4BCNR1 | |
| SCHEMBL3250283 | 0.78 | CA1 (0.53) | MAPTRAB9APDE4BHDAC1HDAC8 | |
| SCHEMBL3250292 | 0.78 | CA1 (0.53) | MAPTRAB9APDE4BHDAC1HDAC8 | |
| SCHEMBL9815578 | 0.78 | CES2 (0.57) | THRBFNTAFNTBPGGT1BLMNA | |
| SCHEMBL23934179 | 0.76 | RAB9A (0.47) | MEN1MAPTRAB9AKMT2AHPGD | |
| SCHEMBL9522917 | 0.75 | HDAC8 (0.69) | MAPTRAB9APDE4BHDAC1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0611786-A1 | Orientation layer for liquid crystals | F. HOFFMANN-LA ROCHE AG (CH) | 1994-08-24 | — | — | EP | disclosed |