Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.43 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL454525 | 0.85 | TSHR (0.44) | TSHRTP53EGLN1EGLN3ALDH1A1 | |
| SCHEMBL454524 | 0.85 | TSHR (0.44) | TSHRTP53EGLN1EGLN3ALDH1A1 | |
| SCHEMBL19379407 | 0.85 | TSHR (0.44) | TSHRTP53EGLN1EGLN3ALDH1A1 | |
| SCHEMBL12486634 | 0.76 | LMNA (0.35) | PTGS1 | |
| SCHEMBL12486635 | 0.76 | LMNA (0.35) | PTGS1 | |
| SCHEMBL28904990 | 0.76 | TSHR (0.75) | TSHRTP53EGLN1EGLN3ALDH1A1 | |
| SCHEMBL1603051 | 0.72 | TSHR (0.50) | TSHRTP53EGLN1EGLN3ALDH1A1 | |
| SCHEMBL1603050 | 0.72 | TSHR (0.50) | TSHRTP53EGLN1EGLN3ALDH1A1 | |
| SCHEMBL2928506 | 0.70 | PTGS1 (0.43) | TSHRALDH1A1ALOX15RECQLHSD17B10 | |
| SCHEMBL2931476 | 0.70 | PTGS1 (0.43) | TSHRALDH1A1ALOX15RECQLHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250037787-A1 | CONCENTRATION BOUNDS IN LARGE NETWORKS | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2025-01-30 | — | — | US | disclosed |
| US-7869957-B2 | Methods and systems to identify operational reaction pathways | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2011-01-11 | — | — | US | disclosed |