Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | GFER | P55789 | 1/20 | 0.54 |
| ▸ | NGLY1 | Q96IV0 | 1/20 | 0.54 |
| ▸ | FABP4 | P15090 | 1/20 | 0.53 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.49 |
| ▸ | AKR1C2 | P52895 | 4/20 | 0.49 |
| ▸ | CTSV | O60911 | 3/20 | 0.47 |
| ▸ | CTSL | P07711 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.42 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8833788 | 0.84 | MAPT (0.67) | MAPTGFERNGLY1FABP4AKR1C3 | |
| SCHEMBL351705 | 0.80 | MAPT (0.79) | MAPTGFERNGLY1FABP4AKR1C3 | |
| SCHEMBL9172301 | 0.78 | MAPT (0.76) | MAPTGFERNGLY1FABP4AKR1C3 | |
| SCHEMBL9409097 | 0.76 | MAPT (0.57) | MAPTGFERNGLY1FABP4AKR1C3 | |
| SCHEMBL28324640 | 0.73 | HMGB1 (0.45) | ALDH1A1HPGDGAATHRBHSD17B10 | |
| Hydrochloric Acid SCHEMBL28298843 | 0.73 | MAPT (0.73) | MAPTGFERNGLY1FABP4AKR1C3 | |
| SCHEMBL2723037 | 0.73 | SIRT2 (0.58) | MAPTGFERNGLY1FABP4KDM4E | |
| SCHEMBL27701802 | 0.73 | IDO1 (0.55) | MAPTGFERNGLY1AKR1C3AKR1C2 | |
| SCHEMBL8002116 | 0.72 | MAPT (0.67) | MAPTGFERNGLY1FABP4AKR1C3 | |
| SCHEMBL1520973 | 0.72 | MAPT (0.56) | MAPTGFERNGLY1FABP4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0600832-A1 | Derivatives of diamino benzoic and diamino phthalic acid und their use as protein linase inhibitors | CIBA-GEIGY AG (CH) | 1994-06-08 | — | — | EP | claimed |
| EP-0600832-A1 | Derivatives of diamino benzoic and diamino phthalic acid und their use as protein linase inhibitors | CIBA-GEIGY AG (CH) | 1994-06-08 | — | — | EP | disclosed |