Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | RAB9A | P51151 | 4/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.57 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | GAA | P10253 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9409039 | 0.95 | SIRT2 (0.56) | MEN1KMT2ARAB9ATHRBSLC2A1 | |
| SCHEMBL9409084 | 0.85 | SIRT2 (0.73) | MEN1KMT2ASIRT2CA1CA2 | |
| SCHEMBL12124929 | 0.81 | RAB9A (0.69) | MEN1KMT2ARAB9ATHRBSLC2A1 | |
| SCHEMBL9409193 | 0.81 | CDC25B (0.60) | MEN1KMT2ARAB9ATHRBLMNA | |
| SCHEMBL9409044 | 0.80 | MAPT (0.56) | MEN1KMT2ARAB9ASIRT2LMNA | |
| SCHEMBL9409101 | 0.78 | MAPT (0.54) | MEN1KMT2ARAB9ASIRT2LMNA | |
| SCHEMBL8834550 | 0.78 | EGFR (0.60) | MEN1KMT2ARAB9ATHRBSLC2A1 | |
| SCHEMBL2255472 | 0.77 | MAPK13 (0.60) | MEN1KMT2ARAB9ATHRBSLC2A1 | |
| SCHEMBL9409210 | 0.77 | SIRT2 (0.58) | RAB9ATHRBSIRT2HPGDMAPT | |
| SCHEMBL9409092 | 0.77 | CDC25B (0.63) | KMT2ARAB9ALMNAHPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0600832-A1 | Derivatives of diamino benzoic and diamino phthalic acid und their use as protein linase inhibitors | CIBA-GEIGY AG (CH) | 1994-06-08 | — | — | EP | disclosed |