Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9409210 | 0.88 | SIRT2 (0.58) | SIRT2KDM4EHPGDMAPTALDH1A1 | |
| SCHEMBL9409039 | 0.86 | SIRT2 (0.56) | SIRT2KMT2AKDM4EMEN1HPGD | |
| SCHEMBL9409057 | 0.85 | MEN1 (0.57) | SIRT2KMT2AKDM4EMEN1HPGD | |
| SCHEMBL9409094 | 0.84 | SIRT2 (0.54) | SIRT2KMT2AKDM4EMEN1HPGD | |
| SCHEMBL9409104 | 0.83 | SIRT2 (0.52) | SIRT2KMT2AKDM4EMEN1HPGD | |
| SCHEMBL9409132 | 0.83 | AKR1C3 (0.55) | SIRT2KMT2AKDM4EMEN1MAPT | |
| SCHEMBL9409059 | 0.83 | ALDH1A1 (0.58) | SIRT2KMT2AMEN1MAPTROCK1 | |
| SCHEMBL9409202 | 0.83 | MAPT (0.64) | SIRT2MAPTALDH1A1GAAHSD17B10 | |
| SCHEMBL9409067 | 0.82 | AKR1C3 (0.60) | SIRT2KMT2AKDM4EMEN1MAPT | |
| SCHEMBL9409188 | 0.82 | SIRT2 (0.51) | SIRT2KMT2AKDM4EMEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0600832-A1 | Derivatives of diamino benzoic and diamino phthalic acid und their use as protein linase inhibitors | CIBA-GEIGY AG (CH) | 1994-06-08 | — | — | EP | disclosed |