Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.47 |
| ▸ | RAB9A | P51151 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | NQO2 | P16083 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9409165 | 1.00 | ALDH1A1 (0.47) | ALDH1A1RAB9AMAPTMAPK1L3MBTL1 | |
| SCHEMBL10177473 | 0.79 | ALDH1A1 (0.53) | ALDH1A1RAB9AMAPTMAPK1L3MBTL1 | |
| SCHEMBL1342675 | 0.79 | ALDH1A1 (0.53) | ALDH1A1RAB9AMAPTMAPK1L3MBTL1 | |
| SCHEMBL1342671 | 0.79 | ALDH1A1 (0.53) | ALDH1A1RAB9AMAPTMAPK1L3MBTL1 | |
| SCHEMBL12449495 | 0.78 | SMN1; SMN2 (0.47) | ALDH1A1RAB9AMAPTMAPK1L3MBTL1 | |
| SCHEMBL9514545 | 0.78 | SMN1; SMN2 (0.43) | ALDH1A1RAB9AMAPTMAPK1L3MBTL1 | |
| SCHEMBL4901564 | 0.78 | SMN1; SMN2 (0.47) | ALDH1A1RAB9AMAPTMAPK1L3MBTL1 | |
| SCHEMBL9514535 | 0.78 | SMN1; SMN2 (0.43) | ALDH1A1RAB9AMAPTMAPK1L3MBTL1 | |
| SCHEMBL4901552 | 0.78 | SMN1; SMN2 (0.47) | ALDH1A1RAB9AMAPTMAPK1L3MBTL1 | |
| SCHEMBL11756950 | 0.76 | CES2 (0.46) | ALDH1A1MAPTL3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9260448-B2 | Thienopyrimidinone derivatives as mGluR1 antagonists | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2016-02-16 | — | — | US | disclosed |
| US-20140228565-A1 | THIENOPYRIMIDINONE DERIVATIVES AS mGluR1 ANTAGONISTS | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2014-08-14 | — | — | US | disclosed |
| EP-0584797-A2 | Novel cephalosporin compounds and processes for the preparation thereof | LUCKY LTD. (KR) | 1994-03-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140228565-A1 | THIENOPYRIMIDINONE DERIVATIVES AS mGluR1 ANTAGONISTS | GRM1, GRIN1, GRM2 | ALDH1A1 531/4885RAB9A 845/4885MAPT 224/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.