Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | DRD3 | P35462 | 2/20 | 0.44 |
| ▸ | DRD2 | P14416 | 2/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.43 |
| ▸ | PRKACA | P17612 | 1/20 | 0.41 |
| ▸ | PRKACG | P22612 | 1/20 | 0.41 |
| ▸ | PRKACB | P22694 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9415854 | 1.00 | ALDH1A1 (0.46) | ALDH1A1LMNAMAPTHTR2ADRD3 | |
| Hydrochloric Acid SCHEMBL9409523 | 0.99 | ALDH1A1 (0.46) | ALDH1A1LMNAMAPTHTR2ADRD3 | |
| Hydrochloric Acid SCHEMBL9409352 | 0.99 | ALDH1A1 (0.46) | ALDH1A1LMNAMAPTHTR2ADRD3 | |
| Hydrochloric Acid SCHEMBL9409468 | 0.93 | ALDH1A1 (0.44) | ALDH1A1LMNAMAPTHTR2ADRD3 | |
| Hydrochloric Acid SCHEMBL9409499 | 0.89 | ALDH1A1 (0.46) | ALDH1A1LMNAMAPTHTR2ADRD3 | |
| Hydrochloric Acid SCHEMBL9409637 | 0.89 | ALDH1A1 (0.42) | ALDH1A1LMNAMAPTHTR2ADRD3 | |
| Hydrochloric Acid SCHEMBL9409513 | 0.88 | MAPT (0.42) | ALDH1A1LMNAMAPTHTR2ADRD3 | |
| SCHEMBL9409598 | 0.87 | DGAT1 (0.47) | ALDH1A1LMNAMAPTHTR2ADRD3 | |
| Hydrochloric Acid SCHEMBL9409614 | 0.87 | ALDH1A1 (0.41) | ALDH1A1LMNAMAPTHTR2ADRD3 | |
| Hydrochloric Acid SCHEMBL9409362 | 0.86 | TLR2 (0.48) | SMYD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0604800-A1 | 4- 4- 4-(carboxyalkyl)-phenyl amino carbonyl -phenyl -piperedines as aggregation inhibitors | Dr. Karl Thomae GmbH (DE) | 1994-07-06 | — | — | EP | claimed |
| JP-6239817-A | — | — | None | — | — | JP | disclosed |
| JP-H06239817-A | CARBOXYLIC ACID DERIVATIVE, PHARMACEUTICAL COMPOSITION CONTAINING THE DERIVATIVE AND PREPARATION THEREOF | DR KARL THOMAE GMBH | 1994-08-30 | — | — | JP | disclosed |
| EP-0604800-A1 | 4- 4- 4-(carboxyalkyl)-phenyl amino carbonyl -phenyl -piperedines as aggregation inhibitors | Dr. Karl Thomae GmbH (DE) | 1994-07-06 | — | — | EP | disclosed |