Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | DRD3 | P35462 | 2/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9409405 | 0.99 | DGAT1 (0.46) | DGAT1ITGB3ITGA2BALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL9409460 | 0.99 | DGAT1 (0.46) | DGAT1ITGB3ITGA2BALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL9409456 | 0.92 | BMPR1B (0.46) | — | |
| Hydrochloric Acid SCHEMBL9409645 | 0.92 | HDAC3 (0.45) | DGAT1ITGB3ITGA2BALDH1A1LMNA | |
| SCHEMBL9409367 | 0.87 | ALDH1A1 (0.46) | ALDH1A1LMNAMAPTHDAC3HDAC4 | |
| SCHEMBL9415854 | 0.87 | ALDH1A1 (0.46) | ALDH1A1LMNAMAPTHDAC3HDAC4 | |
| Hydrochloric Acid SCHEMBL9409437 | 0.87 | DGAT1 (0.49) | DGAT1HDAC3HDAC4HDAC1HDAC7 | |
| Hydrochloric Acid SCHEMBL9409523 | 0.86 | ALDH1A1 (0.46) | ALDH1A1LMNAMAPTHDAC3HDAC4 | |
| Hydrochloric Acid SCHEMBL9409352 | 0.86 | ALDH1A1 (0.46) | ALDH1A1LMNAMAPTHDAC3HDAC4 | |
| SCHEMBL4175744 | 0.86 | RAB9A (0.53) | ALDH1A1MAPTHDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0604800-A1 | 4- 4- 4-(carboxyalkyl)-phenyl amino carbonyl -phenyl -piperedines as aggregation inhibitors | Dr. Karl Thomae GmbH (DE) | 1994-07-06 | — | — | EP | claimed |
| EP-0604800-A1 | 4- 4- 4-(carboxyalkyl)-phenyl amino carbonyl -phenyl -piperedines as aggregation inhibitors | Dr. Karl Thomae GmbH (DE) | 1994-07-06 | — | — | EP | disclosed |