Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.40 |
| ▸ | CCR1 | P32246 | 4/20 | 0.39 |
| ▸ | NAMPT | P43490 | 2/20 | 0.37 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9409591 | 0.85 | HRH3 (0.41) | HRH3CCR1NAMPTP2RY14KDM1A | |
| SCHEMBL9409512 | 0.84 | FFAR1 (0.42) | HRH3NAMPTKDM4EMAPTMAPK1 | |
| SCHEMBL9409592 | 0.81 | CYP4Z1 (0.39) | HRH3CCR1NAMPTP2RY14EPHX2 | |
| Hydrochloric Acid SCHEMBL27412437 | 0.79 | USP25 (0.39) | HRH3EPHX2GPR88 | |
| Hydrochloric Acid SCHEMBL7511725 | 0.76 | KDM1A (0.43) | NAMPTP2RY14TLR9TLR8TLR7 | |
| SCHEMBL25030059 | 0.76 | NAMPT (0.54) | HRH3NAMPTKDM4EMAPT | |
| SCHEMBL10243175 | 0.75 | MAPT (0.50) | NAMPTP2RY14MAPTTLR9TLR8 | |
| SCHEMBL7518442 | 0.74 | P2RY14 (0.43) | CCR1NAMPTP2RY14MAPTTLR9 | |
| SCHEMBL2414763 | 0.72 | P2RY14 (0.44) | NAMPTP2RY14MAPTTLR9TLR8 | |
| SCHEMBL2452371 | 0.70 | KDM1A (0.48) | NAMPTP2RY14TLR9TLR8TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1094035-A | Carboxylic acid derivative contains pharmaceutical composition of these compounds and preparation method thereof | THOMAE GMBH DR K (DE) | 1994-10-26 | — | — | CN | disclosed |
| EP-0604800-A1 | 4- 4- 4-(carboxyalkyl)-phenyl amino carbonyl -phenyl -piperedines as aggregation inhibitors | Dr. Karl Thomae GmbH (DE) | 1994-07-06 | — | — | EP | disclosed |