Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4Z1 | Q86W10 | 3/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.37 |
| ▸ | CA2 | P00918 | 3/20 | 0.37 |
| ▸ | CCR1 | P32246 | 4/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.34 |
| ▸ | CYP4F11 | Q9HBI6 | 1/20 | 0.33 |
| ▸ | CYP4F12 | Q9HCS2 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 2/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9409591 | 0.82 | HRH3 (0.41) | HRH3CCR1P2RY14NAMPTEPHX2 | |
| SCHEMBL9409512 | 0.81 | FFAR1 (0.42) | HRH3CA1CA2NAMPTEPHX2 | |
| SCHEMBL9409503 | 0.81 | HRH3 (0.40) | HRH3CCR1P2RY14NAMPTEPHX2 | |
| SCHEMBL25030059 | 0.73 | NAMPT (0.54) | HRH3NAMPT | |
| SCHEMBL10243175 | 0.72 | MAPT (0.50) | P2RY14NAMPTEPHX2 | |
| SCHEMBL7518442 | 0.72 | P2RY14 (0.43) | CCR1P2RY14NAMPTEPHX2 | |
| Hydrochloric Acid SCHEMBL7511725 | 0.71 | KDM1A (0.43) | P2RY14NAMPTEPHX2 | |
| SCHEMBL571076 | 0.70 | P2RY14 (0.45) | P2RY14NAMPTEPHX2 | |
| SCHEMBL2414763 | 0.69 | P2RY14 (0.44) | P2RY14NAMPTEPHX2 | |
| SCHEMBL20705482 | 0.67 | RAB9A (0.50) | CCR1P2RY14NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0604800-A1 | 4- 4- 4-(carboxyalkyl)-phenyl amino carbonyl -phenyl -piperedines as aggregation inhibitors | Dr. Karl Thomae GmbH (DE) | 1994-07-06 | — | — | EP | disclosed |