Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | CCR1 | P32246 | 5/20 | 0.39 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | RBP4 | P02753 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 2/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9409503 | 0.85 | HRH3 (0.40) | HRH3CCR1P2RY14KDM1ANAMPT | |
| SCHEMBL9409512 | 0.85 | FFAR1 (0.42) | HRH3NAMPTEPHX2 | |
| SCHEMBL9409592 | 0.82 | CYP4Z1 (0.39) | HRH3CCR1P2RY14NAMPTEPHX2 | |
| SCHEMBL25030059 | 0.76 | NAMPT (0.54) | HRH3NAMPT | |
| SCHEMBL10243175 | 0.76 | MAPT (0.50) | P2RY14KDM1ANAMPTEPHX2 | |
| SCHEMBL7518442 | 0.75 | P2RY14 (0.43) | CCR1P2RY14RBP4KDM1ANAMPT | |
| Hydrochloric Acid SCHEMBL7511725 | 0.74 | KDM1A (0.43) | P2RY14RBP4KDM1ANAMPTEPHX2 | |
| SCHEMBL9409547 | 0.73 | NAMPT (0.56) | KDM1ANAMPTLMNA | |
| SCHEMBL2414763 | 0.72 | P2RY14 (0.44) | P2RY14RBP4KDM1ANAMPTEPHX2 | |
| SCHEMBL15254117 | 0.72 | P2RY14 (0.56) | CCR1P2RY14RBP4KDM1ANAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0604800-A1 | 4- 4- 4-(carboxyalkyl)-phenyl amino carbonyl -phenyl -piperedines as aggregation inhibitors | Dr. Karl Thomae GmbH (DE) | 1994-07-06 | — | — | EP | disclosed |