Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.42 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27099790 | 0.88 | TSHR (0.52) | RORCUSP30GPR119SCD5TSHR | |
| SCHEMBL9409426 | 0.88 | PKM (0.48) | RORCKMT2AMEN1TSHRALOX15 | |
| SCHEMBL30127217 | 0.86 | NR1H2 (0.47) | RORCKMT2AMEN1USP30SCD5 | |
| SCHEMBL31566836 | 0.83 | CYP11B2 (0.47) | RORCUSP30GPR119SCD5HDAC2 | |
| SCHEMBL23411856 | 0.82 | GPR119 (0.55) | KMT2AMEN1GPR119TSHRALOX15 | |
| Iodide SCHEMBL31566581 | 0.81 | HDAC2 (0.41) | RORCKMT2AMEN1USP30SCD5 | |
| SCHEMBL15961875 | 0.81 | KMT2A (0.45) | RORCKMT2AMEN1GPR119TSHR | |
| SCHEMBL3246933 | 0.80 | TSHR (0.57) | RORCKMT2AMEN1USP30GPR119 | |
| SCHEMBL19459178 | 0.79 | ESR2 (0.48) | RORCKMT2AMEN1GPR119TSHR | |
| SCHEMBL13608428 | 0.79 | GPR119 (0.53) | KMT2AMEN1GPR119TSHRALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0604800-A1 | 4- 4- 4-(carboxyalkyl)-phenyl amino carbonyl -phenyl -piperedines as aggregation inhibitors | Dr. Karl Thomae GmbH (DE) | 1994-07-06 | — | — | EP | disclosed |