Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | CA7 | P43166 | 3/20 | 0.38 |
| ▸ | CTSK | P43235 | 5/20 | 0.36 |
| ▸ | CTSS | P25774 | 4/20 | 0.36 |
| ▸ | CA12 | O43570 | 3/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | APLNR | P35414 | 1/20 | 0.30 |
| ▸ | CA4 | P22748 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15254162 | 1.00 | CA1 (0.38) | CA1CA2CA7CTSKCTSS | |
| SCHEMBL14778520 | 0.85 | CA1 (0.41) | CA1CA2CA7CTSKCTSS | |
| SCHEMBL14779061 | 0.85 | CA1 (0.41) | CA1CA2CA7CTSKCTSS | |
| SCHEMBL835634 | 0.83 | CA12 (0.37) | CA1CA2CA7CTSKCTSS | |
| SCHEMBL14780357 | 0.77 | CA12 (0.36) | CA1CA2CA7CTSKCTSS | |
| SCHEMBL7401688 | 0.77 | CTSL (0.41) | CA1CA2CA7CTSKCTSS | |
| SCHEMBL14780296 | 0.77 | CA1 (0.37) | CA1CA2CA7CTSKCTSS | |
| SCHEMBL2732000 | 0.76 | TDP1 (0.35) | CA1CA2CA7CTSKCTSS | |
| SCHEMBL14778691 | 0.74 | CA1 (0.40) | CA1CA2CA7CTSKCTSS | |
| SCHEMBL14779117 | 0.73 | CTSK (0.45) | CA1CA2CA7CTSKCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0618221-A2 | Heterocyclic inhibitors of farnesyl protein transferase | BRISTOL-MYERS SQUIBB COMPANY (US) | 1994-10-05 | — | — | EP | disclosed |