Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28336410 | 0.75 | S1PR1 (0.36) | ALDH1A1LMNAS1PR1 | |
| SCHEMBL5405731 | 0.73 | MITF (0.65) | MITFALDH1A1PKMKMT2ALMNA | |
| SCHEMBL3964672 | 0.72 | AGTR1 (0.46) | ALDH1A1KMT2AS1PR1 | |
| SCHEMBL27528516 | 0.72 | AGTR1 (0.46) | ALDH1A1KMT2AS1PR1 | |
| SCHEMBL543481 | 0.71 | AGTR1 (0.46) | ALDH1A1KMT2AS1PR1 | |
| SCHEMBL31433442 | 0.71 | AGTR1 (0.46) | ALDH1A1KMT2AS1PR1 | |
| SCHEMBL9088435 | 0.71 | MITF (0.55) | MITFALDH1A1PKMKMT2AGAA | |
| SCHEMBL4860544 | 0.71 | ALDH1A1 (0.69) | MITFALDH1A1PKMKMT2A | |
| SCHEMBL2445825 | 0.69 | ALDH1A1 (0.61) | MITFALDH1A1PKMKMT2ALMNA | |
| SCHEMBL14181603 | 0.67 | ALDH1A1 (0.73) | MITFALDH1A1PKMKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0621269-A1 | Alkyl substituted nitroimidazole acetic acids | ELI LILLY AND COMPANY (US) | 1994-10-26 | — | — | EP | claimed |