Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | QDPR | P09417 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 6/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.37 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9411386 | 0.91 | ACHE (0.51) | ACHECYP2C9CYP2C19MAPK14QDPR | |
| SCHEMBL9411304 | 0.89 | ACHE (0.45) | ACHECYP2C9CYP2C19MAPK14QDPR | |
| Fumaric Acid SCHEMBL9411339 | 0.80 | ACHE (0.56) | ACHEMEN1KMT2A | |
| Fumaric Acid SCHEMBL9411345 | 0.80 | ACHE (0.56) | ACHEMEN1KMT2A | |
| SCHEMBL9411531 | 0.80 | ACHE (0.63) | ACHEMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8919000 | 0.80 | TDP1 (0.36) | ACHEALDH1A1APOBEC3AAPOBEC3GKDM4E | |
| SCHEMBL8917774 | 0.79 | P2RX3 (0.37) | ACHEMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL1614082 | 0.74 | SMN1; SMN2 (0.55) | CYP2C19MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL9411493 | 0.74 | ACHE (0.53) | ACHE | |
| SCHEMBL9411643 | 0.72 | ACHE (0.62) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0602242-A1 | BENZISOXAZOLE COMPOUND AND USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1994-06-22 | — | — | EP | disclosed |