Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 7/20 | 0.52 |
| ▸ | ACHE | P22303 | 7/20 | 0.52 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | DRD4 | P21917 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9411606 | 0.91 | ACHE (0.62) | ACHEDRD2DRD4 | |
| SCHEMBL9411372 | 0.85 | ACHE (0.49) | ACHEDRD2DRD4SLC6A4SLC6A3 | |
| SCHEMBL9411462 | 0.84 | SLC6A2 (0.57) | ACHEDRD2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9411640 | 0.84 | ACHE (0.50) | ACHEDRD2DRD4SLC6A2SLC6A4 | |
| Fumaric Acid SCHEMBL9411250 | 0.83 | ACHE (0.52) | MCHR1ACHEDRD2DRD4SLC6A2 | |
| Fumaric Acid SCHEMBL9411247 | 0.83 | ACHE (0.52) | MCHR1ACHEDRD2DRD4SLC6A2 | |
| SCHEMBL9411261 | 0.80 | ACHE (0.70) | ACHEDRD2DRD4 | |
| SCHEMBL9411323 | 0.79 | SLC6A2 (0.54) | ACHEDRD2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9411273 | 0.79 | ACHE (0.79) | ACHEDRD2DRD4 | |
| SCHEMBL9411404 | 0.79 | OPRM1 (0.43) | ACHEDRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0602242-A1 | BENZISOXAZOLE COMPOUND AND USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1994-06-22 | — | — | EP | disclosed |