Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 10/20 | 0.41 |
| ▸ | HTR2A | P28223 | 9/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9411404 | 0.92 | OPRM1 (0.43) | ACHEOPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL9411464 | 0.88 | ACHE (0.47) | ACHE | |
| SCHEMBL9411555 | 0.88 | ACHE (0.41) | ACHEOPRM1OPRD1OPRK1OPRL1 | |
| Fumaric Acid SCHEMBL9411333 | 0.84 | ACHE (0.43) | ACHEOPRM1OPRD1OPRK1OPRL1 | |
| Fumaric Acid SCHEMBL9411328 | 0.84 | ACHE (0.43) | ACHEOPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL9411617 | 0.84 | HTR2A (0.42) | ACHEDRD3HTR2A | |
| SCHEMBL9411525 | 0.83 | ACHE (0.47) | ACHEDRD3HTR2ADRD2 | |
| SCHEMBL9411644 | 0.83 | ACHE (0.41) | ACHEOPRM1OPRD1OPRK1OPRL1 | |
| Fumaric Acid SCHEMBL9411620 | 0.82 | ACHE (0.48) | ACHEDRD3HTR2A | |
| SCHEMBL9411358 | 0.82 | ACHE (0.48) | ACHEOPRM1OPRD1OPRK1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0602242-A1 | BENZISOXAZOLE COMPOUND AND USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1994-06-22 | — | — | EP | disclosed |