Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.47 |
| ▸ | HTR1A | P08908 | 2/20 | 0.45 |
| ▸ | DRD2 | P14416 | 2/20 | 0.45 |
| ▸ | HTR2A | P28223 | 2/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | HRH1 | P35367 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | HTR6 | P50406 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9411464 | 0.95 | ACHE (0.47) | ACHEKCNH2 | |
| SCHEMBL9411644 | 0.88 | ACHE (0.41) | ACHEHTR2AHRH3DRD3 | |
| SCHEMBL9411496 | 0.85 | HTR1A (0.55) | ACHEKCNH2HTR1ADRD2HTR2A | |
| SCHEMBL9411537 | 0.84 | DRD2 (0.55) | ACHEDRD2HTR2AHTR6 | |
| SCHEMBL9411555 | 0.83 | ACHE (0.41) | ACHEHTR2ADRD3 | |
| SCHEMBL9411529 | 0.83 | ACHE (0.42) | ACHEDRD2HTR2ADRD3 | |
| SCHEMBL9411659 | 0.82 | HTR1A (0.51) | ACHEKCNH2HTR1ADRD2HTR2A | |
| SCHEMBL9411577 | 0.82 | HTR1A (0.53) | ACHEKCNH2HTR1ADRD2HTR2A | |
| SCHEMBL9411473 | 0.81 | ACHE (0.56) | ACHEDRD2HTR2AHTR6 | |
| SCHEMBL9411590 | 0.81 | ACHE (0.46) | ACHEKCNH2HTR1ADRD2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0602242-A1 | BENZISOXAZOLE COMPOUND AND USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1994-06-22 | — | — | EP | disclosed |