Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.41 |
| ▸ | ACP1 | P24666 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9412477 | 0.94 | HDAC1 (0.42) | BRD4HDAC1HDAC8 | |
| SCHEMBL9412609 | 0.93 | HDAC1 (0.44) | BRD4HDAC1 | |
| Bromide SCHEMBL9412576 | 0.91 | ITGB3 (0.47) | TSHRBRD4CREBBPUSP2HTT | |
| SCHEMBL9412697 | 0.89 | SMN1; SMN2 (0.47) | TSHRBRD4HDAC1HPGD | |
| SCHEMBL9412515 | 0.86 | JAK2 (0.47) | TSHRBRD4 | |
| Bromide SCHEMBL9412436 | 0.86 | ITGB3 (0.47) | BRD4HDAC1 | |
| SCHEMBL9412544 | 0.85 | HDAC1 (0.48) | BRD4CYP2D6CYP2C9ALDH1A1HDAC1 | |
| Bromide SCHEMBL9412577 | 0.85 | ITGB3 (0.49) | BRD4HDAC1HDAC8 | |
| SCHEMBL9412623 | 0.84 | MAPT (0.46) | BRD4 | |
| SCHEMBL9412591 | 0.82 | MAPT (0.51) | TSHRUSP2HTTHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0611660-A2 | Condensed 5-membered heterocycles, process for their preparation and medicines containing these compounds | Dr. Karl Thomae GmbH (DE) | 1994-08-24 | — | — | EP | disclosed |