Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | GNRHR | P30968 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL9412705 | 0.90 | MEN1 (0.50) | ALDH1A1LMNATSHRPKMMEN1 | |
| SCHEMBL9412623 | 0.82 | MAPT (0.46) | MAPTGAASMN1; SMN2 | |
| SCHEMBL9412664 | 0.80 | PDE3B (0.42) | ALDH1A1LMNATSHRPKMCNR2 | |
| SCHEMBL9412731 | 0.80 | KDM4E (0.52) | ALDH1A1MEN1KMT2ARECQLHTT | |
| SCHEMBL9412511 | 0.79 | MAPT (0.45) | LMNAMAPTGAAHTTSMN1; SMN2 | |
| SCHEMBL9412497 | 0.79 | CNR2 (0.42) | ALDH1A1LMNATSHRMEN1KMT2A | |
| SCHEMBL9412665 | 0.78 | MAPT (0.45) | MAPTGAASMN1; SMN2 | |
| SCHEMBL9412536 | 0.77 | ITGB3 (0.46) | MAPTGAASMN1; SMN2 | |
| SCHEMBL9412452 | 0.77 | MAPT (0.44) | MAPTGAASMN1; SMN2 | |
| SCHEMBL9412685 | 0.77 | ITGB3 (0.38) | PKMMAPTSMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0611660-A2 | Condensed 5-membered heterocycles, process for their preparation and medicines containing these compounds | Dr. Karl Thomae GmbH (DE) | 1994-08-24 | — | — | EP | disclosed |