Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 6/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.46 |
| ▸ | ACSS2 | Q9NR19 | 4/20 | 0.45 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | IDH1 | O75874 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9412623 | 0.93 | MAPT (0.46) | ITGB3ITGA2BITGA2ROCK2GAA | |
| SCHEMBL9412511 | 0.88 | MAPT (0.45) | ITGB3ITGA2BITGA2ROCK2GAA | |
| SCHEMBL9412665 | 0.88 | MAPT (0.45) | ITGB3ITGA2BITGA2ROCK2GAA | |
| SCHEMBL9412452 | 0.87 | MAPT (0.44) | ITGB3ITGA2BITGA2ROCK2GAA | |
| SCHEMBL9412685 | 0.85 | ITGB3 (0.38) | ITGB3ITGA2BMAPTSMN1; SMN2POLB | |
| SCHEMBL9412599 | 0.84 | HTR4 (0.38) | ITGB3ITGA2BMAPT | |
| SCHEMBL9412475 | 0.84 | HTR4 (0.42) | ITGB3ITGA2BROCK2MAPTSMN1; SMN2 | |
| SCHEMBL9412438 | 0.84 | ITGB3 (0.38) | ITGB3ITGA2BITGA2MAPTPOLB | |
| SCHEMBL9412586 | 0.84 | RORC (0.46) | ITGB3ITGA2BITGA2ROCK2IDH1 | |
| SCHEMBL9412515 | 0.84 | JAK2 (0.47) | ITGB3ITGA2BITGA2ROCK2IDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0611660-A2 | Condensed 5-membered heterocycles, process for their preparation and medicines containing these compounds | Dr. Karl Thomae GmbH (DE) | 1994-08-24 | — | — | EP | disclosed |