Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 9/20 | 0.55 |
| ▸ | FGFR4 | P22455 | 9/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.45 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.45 |
| ▸ | FDPS | P14324 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
| ▸ | ADCY5 | O95622 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9412574 | 0.85 | FGFR1 (0.41) | FGFR1FGFR4HDAC6P2RX7GSK3B | |
| SCHEMBL22326706 | 0.73 | FDPS (0.41) | FGFR1FGFR4HDAC6P2RX7FDPS | |
| SCHEMBL8906057 | 0.72 | FDPS (0.41) | FGFR1FGFR4HDAC6P2RX7FDPS | |
| SCHEMBL8503725 | 0.68 | FGFR1 (0.43) | FGFR1FGFR4HDAC6P2RX7FDPS | |
| SCHEMBL23885424 | 0.68 | P2RX7 (0.66) | FGFR1FGFR4HDAC6P2RX7FDPS | |
| SCHEMBL3273477 | 0.67 | GSK3B (0.49) | FGFR1FGFR4HDAC6P2RX7FDPS | |
| SCHEMBL21591519 | 0.67 | FGFR1 (0.51) | FGFR1FGFR4HDAC6P2RX7FDPS | |
| SCHEMBL9412748 | 0.67 | FGFR1 (0.48) | FGFR1FGFR4HDAC6P2RX7FDPS | |
| SCHEMBL30449152 | 0.67 | GSK3B (0.52) | FGFR1FGFR4HDAC6P2RX7FDPS | |
| SCHEMBL28020916 | 0.67 | P2RX7 (0.64) | FGFR1FGFR4HDAC6P2RX7FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0590361-A1 | Process for the preparation of 2-amino-6-halopurines | BASF Aktiengesellschaft (DE) | 1994-04-06 | — | — | EP | disclosed |