Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 4/20 | 0.64 |
| ▸ | FDPS | P14324 | 1/20 | 0.56 |
| ▸ | FGFR1 | P11362 | 9/20 | 0.54 |
| ▸ | FGFR4 | P22455 | 9/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.53 |
| ▸ | FLT4 | P35916 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 2/20 | 0.44 |
| ▸ | AHCY | P23526 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23885424 | 0.86 | P2RX7 (0.66) | P2RX7FDPSFGFR1FGFR4HDAC6 | |
| SCHEMBL27713663 | 0.81 | EGFR (0.64) | KDREGFRAHCY | |
| SCHEMBL9545171 | 0.80 | P2RX7 (0.56) | P2RX7FDPSFGFR1FGFR4HDAC6 | |
| SCHEMBL28950122 | 0.80 | KDR (0.46) | P2RX7FLT4KDREGFRAHCY | |
| SCHEMBL7832523 | 0.78 | ADORA2A (0.64) | P2RX7FDPSFGFR1FGFR4HDAC6 | |
| SCHEMBL23323404 | 0.78 | FDPS (0.63) | P2RX7FDPSFGFR1FGFR4HDAC6 | |
| SCHEMBL30254206 | 0.77 | P2RX7 (0.53) | P2RX7FDPSFGFR1FGFR4HDAC6 | |
| SCHEMBL9533818 | 0.77 | P2RX7 (0.56) | P2RX7FDPSFGFR1FGFR4HDAC6 | |
| SCHEMBL9534919 | 0.76 | P2RX7 (0.51) | P2RX7FDPSFGFR1FGFR4HDAC6 | |
| SCHEMBL23436498 | 0.76 | ADORA2A (0.66) | P2RX7FDPSFGFR1FGFR4HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104710424-B | (R) (+) preparation method of 9 (2 hydroxypropyl) adenine | 河南师范大学 | 2017-03-01 | — | — | CN | claimed |
| CN-116332934-A | Synthesis process of tenofovir intermediate | 江苏阿尔法药业股份有限公司 | 2023-06-27 | — | — | CN | disclosed |
| CN-104710424-B | (R) (+) preparation method of 9 (2 hydroxypropyl) adenine | 河南师范大学 | 2017-03-01 | — | — | CN | disclosed |
| CN-104710424-A | Preparation method of (R)-(+)-9-(2-hydroxypropyl) adenine | UNIV HENAN NORMAL | 2015-06-17 | — | — | CN | disclosed |