Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | REN | P00797 | 2/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | YAP1 | P46937 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8800318 | 0.88 | CTSD (0.52) | CTSDRENCTSLCTSB | |
| SCHEMBL8801156 | 0.83 | CTSD (0.77) | CTSDALDH1A1LMNAREN | |
| SCHEMBL8665786 | 0.83 | CTSD (0.48) | CTSDMEN1ALDH1A1LMNAKMT2A | |
| SCHEMBL8801460 | 0.82 | CTSD (0.52) | CTSDRENCTSLCTSB | |
| SCHEMBL8801420 | 0.75 | CTSD (0.78) | CTSDALDH1A1LMNARENCTSL | |
| SCHEMBL9190618 | 0.72 | CTSD (0.54) | CTSDMEN1LMNAKMT2AREN | |
| SCHEMBL8801929 | 0.72 | CTSD (0.82) | CTSDALDH1A1LMNARENCTSL | |
| SCHEMBL10744547 | 0.72 | ALDH1A1 (0.67) | MEN1ALDH1A1LMNAKMT2ACTSL | |
| SCHEMBL7298678 | 0.70 | MME (0.53) | CTSLCTSB | |
| SCHEMBL8664364 | 0.70 | CTSD (0.49) | CTSDCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0601486-A1 | Cis-epoxide derivatives useful as irreversible HIV protease inhibitors and process and intermediates for their preparation | LUCKY LTD. (KR) | 1994-06-15 | — | — | EP | claimed |