Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 1/20 | 0.52 |
| ▸ | CTSB | P07858 | 1/20 | 0.52 |
| ▸ | BACE1 | P56817 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MME | P08473 | 2/20 | 0.43 |
| ▸ | ECE1 | P42892 | 2/20 | 0.43 |
| ▸ | REN | P00797 | 1/20 | 0.42 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8801460 | 0.94 | CTSD (0.52) | CTSDCTSBSMN1; SMN2MMEECE1 | |
| SCHEMBL9412784 | 0.88 | CTSD (0.52) | CTSDCTSBRENCTSL | |
| SCHEMBL8801156 | 0.84 | CTSD (0.77) | CTSDREN | |
| SCHEMBL7298678 | 0.84 | MME (0.53) | CTSBSMN1; SMN2MMEECE1CTSL | |
| SCHEMBL7295499 | 0.84 | CTSL (0.51) | CTSDCTSBMMEECE1CTSL | |
| SCHEMBL9190618 | 0.83 | CTSD (0.54) | CTSDCTSBMMEECE1REN | |
| SCHEMBL8664364 | 0.82 | CTSD (0.49) | CTSDCTSBCAPN1CTSLADORA3 | |
| SCHEMBL8661021 | 0.81 | SMN1; SMN2 (0.48) | CTSBSMN1; SMN2MMEECE1CTSL | |
| SCHEMBL8663687 | 0.81 | CTSD (0.47) | CTSDCTSBMMEECE1CTSL | |
| SCHEMBL8944865 | 0.79 | CTSL (0.50) | CTSDCTSBMMEECE1CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0601486-B1 | Cis-epoxide derivatives useful as irreversible HIV protease inhibitors and process and intermediates for their preparation | LUCKY LTD (KR) | 1997-10-29 | — | — | EP | claimed |