Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.56 |
| ▸ | DRD2 | P14416 | 3/20 | 0.56 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.52 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.52 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.52 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.52 |
| ▸ | MGLL | Q99685 | 1/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 6/20 | 0.49 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3034705 | 0.85 | HTR1A (0.51) | HTR1ADRD2PTGER1PTGER4PTGER3 | |
| SCHEMBL8862483 | 0.83 | HTR1A (0.50) | HTR1ADRD2PTGER1PTGER4PTGER3 | |
| SCHEMBL5255429 | 0.82 | THRA (0.54) | — | |
| SCHEMBL1133196 | 0.81 | THRA (0.56) | MGLL | |
| SCHEMBL1896181 | 0.81 | THRA (0.56) | MGLL | |
| SCHEMBL2895478 | 0.81 | THRA (0.56) | MGLL | |
| SCHEMBL9057460 | 0.80 | HTR1A (0.79) | HTR1ADRD2PTGER1PTGER4PTGER3 | |
| SCHEMBL11349591 | 0.79 | HPGD (0.61) | HTR1ADRD2 | |
| SCHEMBL17197391 | 0.79 | HTR1A (0.79) | HTR1ADRD2PTGER1PTGER4PTGER3 | |
| SCHEMBL5268648 | 0.78 | SIGMAR1 (0.65) | ABCB1ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0600717-A1 | Phenoxyalkylamines, -pyrrolidines and -piperidines for the treatment and prevention of circulatory diseases and psychosis | SANKYO COMPANY LIMITED (JP) | 1994-06-08 | — | — | EP | disclosed |